Electrochemically Activated Screen-Printed Carbon Electrode for Determination of Ibuprofen
In this study, we present a simple, sensitive and selective analytical procedure for the ibuprofen (IBP) analysis using the commercially available screen-printed carbon electrode electrochemically activated (aSPCE) by cyclic voltammetry in 0.1 M NaOH. The quantitative determinations of IBP were carr...
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MDPI AG
2021
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oai:doaj.org-article:57c8eeaf0a2f4e5abf4c2ef7945c61462021-11-11T15:00:32ZElectrochemically Activated Screen-Printed Carbon Electrode for Determination of Ibuprofen10.3390/app112199082076-3417https://doaj.org/article/57c8eeaf0a2f4e5abf4c2ef7945c61462021-10-01T00:00:00Zhttps://www.mdpi.com/2076-3417/11/21/9908https://doaj.org/toc/2076-3417In this study, we present a simple, sensitive and selective analytical procedure for the ibuprofen (IBP) analysis using the commercially available screen-printed carbon electrode electrochemically activated (aSPCE) by cyclic voltammetry in 0.1 M NaOH. The quantitative determinations of IBP were carried out in 0.25 M acetate buffer solution of pH 4.5 ± 0.1 using the differential-pulse voltammetry (DPV). Different experimental parameters for DPV analysis were optimized, including pH and concentration of supporting electrolyte, amplitude (ΔE<sub>A</sub>), scan rate (ν) and modulation time (t<sub>m</sub>). The linear ranges of calibration curve were from 0.50–20.0 and 20.0–500.0 µM. The detection and quantification limits were estimated to be 0.059 and 0.20 µM. The aSPCE displayed satisfactory repeatability, reproducibility, and selectivity. Furthermore, the DPV procedure with the use of aSPCE was used to determination of IBP in pharmaceutical formulations. The results achieved by DPV show satisfactory agreement with those obtained by manufacturers (the relative errors are in the range of 3.1–4.7%).Katarzyna Tyszczuk-RotkoJędrzej KozakAnna WęzińskaMDPI AGarticleelectrochemically activated screen-printed carbon sensoribuprofen determinationdifferential-pulse voltammetrypharmaceutical formulationsTechnologyTEngineering (General). Civil engineering (General)TA1-2040Biology (General)QH301-705.5PhysicsQC1-999ChemistryQD1-999ENApplied Sciences, Vol 11, Iss 9908, p 9908 (2021) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
electrochemically activated screen-printed carbon sensor ibuprofen determination differential-pulse voltammetry pharmaceutical formulations Technology T Engineering (General). Civil engineering (General) TA1-2040 Biology (General) QH301-705.5 Physics QC1-999 Chemistry QD1-999 |
| spellingShingle |
electrochemically activated screen-printed carbon sensor ibuprofen determination differential-pulse voltammetry pharmaceutical formulations Technology T Engineering (General). Civil engineering (General) TA1-2040 Biology (General) QH301-705.5 Physics QC1-999 Chemistry QD1-999 Katarzyna Tyszczuk-Rotko Jędrzej Kozak Anna Węzińska Electrochemically Activated Screen-Printed Carbon Electrode for Determination of Ibuprofen |
| description |
In this study, we present a simple, sensitive and selective analytical procedure for the ibuprofen (IBP) analysis using the commercially available screen-printed carbon electrode electrochemically activated (aSPCE) by cyclic voltammetry in 0.1 M NaOH. The quantitative determinations of IBP were carried out in 0.25 M acetate buffer solution of pH 4.5 ± 0.1 using the differential-pulse voltammetry (DPV). Different experimental parameters for DPV analysis were optimized, including pH and concentration of supporting electrolyte, amplitude (ΔE<sub>A</sub>), scan rate (ν) and modulation time (t<sub>m</sub>). The linear ranges of calibration curve were from 0.50–20.0 and 20.0–500.0 µM. The detection and quantification limits were estimated to be 0.059 and 0.20 µM. The aSPCE displayed satisfactory repeatability, reproducibility, and selectivity. Furthermore, the DPV procedure with the use of aSPCE was used to determination of IBP in pharmaceutical formulations. The results achieved by DPV show satisfactory agreement with those obtained by manufacturers (the relative errors are in the range of 3.1–4.7%). |
| format |
article |
| author |
Katarzyna Tyszczuk-Rotko Jędrzej Kozak Anna Węzińska |
| author_facet |
Katarzyna Tyszczuk-Rotko Jędrzej Kozak Anna Węzińska |
| author_sort |
Katarzyna Tyszczuk-Rotko |
| title |
Electrochemically Activated Screen-Printed Carbon Electrode for Determination of Ibuprofen |
| title_short |
Electrochemically Activated Screen-Printed Carbon Electrode for Determination of Ibuprofen |
| title_full |
Electrochemically Activated Screen-Printed Carbon Electrode for Determination of Ibuprofen |
| title_fullStr |
Electrochemically Activated Screen-Printed Carbon Electrode for Determination of Ibuprofen |
| title_full_unstemmed |
Electrochemically Activated Screen-Printed Carbon Electrode for Determination of Ibuprofen |
| title_sort |
electrochemically activated screen-printed carbon electrode for determination of ibuprofen |
| publisher |
MDPI AG |
| publishDate |
2021 |
| url |
https://doaj.org/article/57c8eeaf0a2f4e5abf4c2ef7945c6146 |
| work_keys_str_mv |
AT katarzynatyszczukrotko electrochemicallyactivatedscreenprintedcarbonelectrodefordeterminationofibuprofen AT jedrzejkozak electrochemicallyactivatedscreenprintedcarbonelectrodefordeterminationofibuprofen AT annawezinska electrochemicallyactivatedscreenprintedcarbonelectrodefordeterminationofibuprofen |
| _version_ |
1718437887753584640 |