Gene co-expression network analysis in human spinal cord highlights mechanisms underlying amyotrophic lateral sclerosis susceptibility

Abstract Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease defined by motor neuron (MN) loss. Multiple genetic risk factors have been identified, implicating RNA and protein metabolism and intracellular transport, among other biological mechanisms. To achieve a systems-level underst...

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Bibliographic Details
Main Authors: Jerry C. Wang, Gokul Ramaswami, Daniel H. Geschwind
Format: article
Language:EN
Published: Nature Portfolio 2021
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Online Access:https://doaj.org/article/57ce8c4e63e04689a29f9c91424b88b9
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