A transcription factor map as revealed by a genome-wide gene expression analysis of whole-blood mRNA transcriptome in multiple sclerosis.

A transcription factor map as revealed by a genome-wide gene expression analysis of whole-blood mRNA transcriptome in multiple sclerosis.

<h4>Background</h4>Several lines of evidence suggest that transcription factors are involved in the pathogenesis of Multiple Sclerosis (MS) but complete mapping of the whole network has been elusive. One of the reasons is that there are several clinical subtypes of MS and transcription f...

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Autores principales: Carlos Riveros, Drew Mellor, Kaushal S Gandhi, Fiona C McKay, Mathew B Cox, Regina Berretta, S Yahya Vaezpour, Mario Inostroza-Ponta, Simon A Broadley, Robert N Heard, Stephen Vucic, Graeme J Stewart, David W Williams, Rodney J Scott, Jeanette Lechner-Scott, David R Booth, Pablo Moscato, ANZgene Multiple Sclerosis Genetics Consortium
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2010
Materias:
Medicine
R
Science
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Acceso en línea:https://doaj.org/article/57cf07fc99e548b88dcd763073a08da1
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