CircRNA Chordc1 protects mice from abdominal aortic aneurysm by contributing to the phenotype and growth of vascular smooth muscle cells

CircRNA Chordc1 protects mice from abdominal aortic aneurysm by contributing to the phenotype and growth of vascular smooth muscle cells

Circular RNAs (circRNAs) have important potential in modulating vascular smooth muscle cell (VSMC) activity, but their roles in abdominal aortic aneurysm (AAA) are unknown. We performed in situ hybridization and immunohistochemistry and determined that circChordc1 (cysteine and histidine-rich domain...

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Autores principales: Xiang He, Xinzhong Li, Yuan Han, Guojun Chen, Tong Xu, Donghua Cai, Yili Sun, Shifei Wang, Yanxian Lai, Zhonghua Teng, Senlin Huang, Wangjun Liao, Yulin Liao, Jianping Bin, Jiancheng Xiu
Formato: article
Lenguaje:EN
Publicado: Elsevier 2022
Materias:
abdominal aortic aneurysm
VSMCs
apoptosis
phenotypic switching
CircRNA
ANXA2
Therapeutics. Pharmacology
RM1-950
Acceso en línea:https://doaj.org/article/57d606b1bb864af6a537cc0c20d1cd38
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