<named-content content-type="genus-species">Escherichia coli</named-content>: Great Diversity around a Common Core
ABSTRACT The 2011 Escherichia coli outbreak in Germany, which resulted in more than 4,000 cases, including 908 cases of hemolytic-uremic syndrome (HUS) and at least 50 deaths, highlighted the genome plasticity of E. coli and the potential for new virulent strains to emerge. The analysis of 170 E. co...
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| Autores principales: | , , , , , |
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| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
American Society for Microbiology
2012
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| Materias: | |
| Acceso en línea: | https://doaj.org/article/57e094e0b43a4bffaff3a5db6b9f083b |
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| Sumario: | ABSTRACT The 2011 Escherichia coli outbreak in Germany, which resulted in more than 4,000 cases, including 908 cases of hemolytic-uremic syndrome (HUS) and at least 50 deaths, highlighted the genome plasticity of E. coli and the potential for new virulent strains to emerge. The analysis of 170 E. coli genome sequences for the presence of nine previously identified protective extraintestinal pathogenic E. coli antigens suggested the feasibility of a combination vaccine as a universal intervention against all pathogenic E. coli strains. IMPORTANCE This article reports on the feasibility of a combination vaccine as a universal intervention against all pathogenic Escherichia coli strains. |
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