<named-content content-type="genus-species">Escherichia coli</named-content>: Great Diversity around a Common Core

ABSTRACT The 2011 Escherichia coli outbreak in Germany, which resulted in more than 4,000 cases, including 908 cases of hemolytic-uremic syndrome (HUS) and at least 50 deaths, highlighted the genome plasticity of E. coli and the potential for new virulent strains to emerge. The analysis of 170 E. co...

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Autores principales:	Danilo G. Moriel, Roberto Rosini, Kate L. Seib, Laura Serino, Mariagrazia Pizza, Rino Rappuoli
Formato:	article
Lenguaje:	EN
Publicado:	American Society for Microbiology 2012
Materias:	Microbiology QR1-502
Acceso en línea:	https://doaj.org/article/57e094e0b43a4bffaff3a5db6b9f083b
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spelling	oai:doaj.org-article:57e094e0b43a4bffaff3a5db6b9f083b2021-11-15T15:39:02Z<named-content content-type="genus-species">Escherichia coli</named-content>: Great Diversity around a Common Core10.1128/mBio.00118-122150-7511https://doaj.org/article/57e094e0b43a4bffaff3a5db6b9f083b2012-07-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mBio.00118-12https://doaj.org/toc/2150-7511ABSTRACT The 2011 Escherichia coli outbreak in Germany, which resulted in more than 4,000 cases, including 908 cases of hemolytic-uremic syndrome (HUS) and at least 50 deaths, highlighted the genome plasticity of E. coli and the potential for new virulent strains to emerge. The analysis of 170 E. coli genome sequences for the presence of nine previously identified protective extraintestinal pathogenic E. coli antigens suggested the feasibility of a combination vaccine as a universal intervention against all pathogenic E. coli strains. IMPORTANCE This article reports on the feasibility of a combination vaccine as a universal intervention against all pathogenic Escherichia coli strains.Danilo G. MorielRoberto RosiniKate L. SeibLaura SerinoMariagrazia PizzaRino RappuoliAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmBio, Vol 3, Iss 3 (2012)
institution	DOAJ
collection	DOAJ
language	EN
topic	Microbiology QR1-502
spellingShingle	Microbiology QR1-502 Danilo G. Moriel Roberto Rosini Kate L. Seib Laura Serino Mariagrazia Pizza Rino Rappuoli <named-content content-type="genus-species">Escherichia coli</named-content>: Great Diversity around a Common Core
description	ABSTRACT The 2011 Escherichia coli outbreak in Germany, which resulted in more than 4,000 cases, including 908 cases of hemolytic-uremic syndrome (HUS) and at least 50 deaths, highlighted the genome plasticity of E. coli and the potential for new virulent strains to emerge. The analysis of 170 E. coli genome sequences for the presence of nine previously identified protective extraintestinal pathogenic E. coli antigens suggested the feasibility of a combination vaccine as a universal intervention against all pathogenic E. coli strains. IMPORTANCE This article reports on the feasibility of a combination vaccine as a universal intervention against all pathogenic Escherichia coli strains.
format	article
author	Danilo G. Moriel Roberto Rosini Kate L. Seib Laura Serino Mariagrazia Pizza Rino Rappuoli
author_facet	Danilo G. Moriel Roberto Rosini Kate L. Seib Laura Serino Mariagrazia Pizza Rino Rappuoli
author_sort	Danilo G. Moriel
title	<named-content content-type="genus-species">Escherichia coli</named-content>: Great Diversity around a Common Core
title_short	<named-content content-type="genus-species">Escherichia coli</named-content>: Great Diversity around a Common Core
title_full	<named-content content-type="genus-species">Escherichia coli</named-content>: Great Diversity around a Common Core
title_fullStr	<named-content content-type="genus-species">Escherichia coli</named-content>: Great Diversity around a Common Core
title_full_unstemmed	<named-content content-type="genus-species">Escherichia coli</named-content>: Great Diversity around a Common Core
title_sort	<named-content content-type="genus-species">escherichia coli</named-content>: great diversity around a common core
publisher	American Society for Microbiology
publishDate	2012
url	https://doaj.org/article/57e094e0b43a4bffaff3a5db6b9f083b
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<named-content content-type="genus-species">Escherichia coli</named-content>: Great Diversity around a Common Core

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