Author Correction: GWAS for male-pattern baldness identifies 71 susceptibility loci explaining 38% of the risk

We have been alerted that in our recent Article the calculations used to transform the heritability from the observed scale to the liability scale did not take into account the individuals in category 2 of the baldness scale, who were removed in our original analysis. This led to an overestimation o...

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Autores principales:	Nicola Pirastu, Peter K. Joshi, Paul S. de Vries, Marilyn C. Cornelis, Paul M. McKeigue, NaNa Keum, Nora Franceschini, Marco Colombo, Edward L. Giovannucci, Athina Spiliopoulou, Lude Franke, Kari E. North, Peter Kraft, Alanna C. Morrison, Tõnu Esko, James F. Wilson
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/57f23b9d9dec4010aaabffaaa41ec2ed
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spelling	oai:doaj.org-article:57f23b9d9dec4010aaabffaaa41ec2ed2021-12-02T13:23:48ZAuthor Correction: GWAS for male-pattern baldness identifies 71 susceptibility loci explaining 38% of the risk10.1038/s41467-018-04857-72041-1723https://doaj.org/article/57f23b9d9dec4010aaabffaaa41ec2ed2018-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04857-7https://doaj.org/toc/2041-1723We have been alerted that in our recent Article the calculations used to transform the heritability from the observed scale to the liability scale did not take into account the individuals in category 2 of the baldness scale, who were removed in our original analysis. This led to an overestimation of the heritability on the liability scale, which should have been 0.62 instead of 0.94. Moreover, in the Title and in the Abstract, we report that we can explain 38% of the risk, while in fact that is the proportion of heritability explained by the loci we discovered. These errors do not substantially change the paper or its conclusions apart from the statement MBP is therefore probably one of the most heritable complex traits. Genome-wide significant associations and pathway analyses are not affected in any way and male-pattern baldness remains less genetically complex than other complex traits. We wish to thank Yap et al. for bringing this to our attention.Nicola PirastuPeter K. JoshiPaul S. de VriesMarilyn C. CornelisPaul M. McKeigueNaNa KeumNora FranceschiniMarco ColomboEdward L. GiovannucciAthina SpiliopoulouLude FrankeKari E. NorthPeter KraftAlanna C. MorrisonTõnu EskoJames F. WilsonNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-1 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Nicola Pirastu Peter K. Joshi Paul S. de Vries Marilyn C. Cornelis Paul M. McKeigue NaNa Keum Nora Franceschini Marco Colombo Edward L. Giovannucci Athina Spiliopoulou Lude Franke Kari E. North Peter Kraft Alanna C. Morrison Tõnu Esko James F. Wilson Author Correction: GWAS for male-pattern baldness identifies 71 susceptibility loci explaining 38% of the risk
description	We have been alerted that in our recent Article the calculations used to transform the heritability from the observed scale to the liability scale did not take into account the individuals in category 2 of the baldness scale, who were removed in our original analysis. This led to an overestimation of the heritability on the liability scale, which should have been 0.62 instead of 0.94. Moreover, in the Title and in the Abstract, we report that we can explain 38% of the risk, while in fact that is the proportion of heritability explained by the loci we discovered. These errors do not substantially change the paper or its conclusions apart from the statement MBP is therefore probably one of the most heritable complex traits. Genome-wide significant associations and pathway analyses are not affected in any way and male-pattern baldness remains less genetically complex than other complex traits. We wish to thank Yap et al. for bringing this to our attention.
format	article
author	Nicola Pirastu Peter K. Joshi Paul S. de Vries Marilyn C. Cornelis Paul M. McKeigue NaNa Keum Nora Franceschini Marco Colombo Edward L. Giovannucci Athina Spiliopoulou Lude Franke Kari E. North Peter Kraft Alanna C. Morrison Tõnu Esko James F. Wilson
author_facet	Nicola Pirastu Peter K. Joshi Paul S. de Vries Marilyn C. Cornelis Paul M. McKeigue NaNa Keum Nora Franceschini Marco Colombo Edward L. Giovannucci Athina Spiliopoulou Lude Franke Kari E. North Peter Kraft Alanna C. Morrison Tõnu Esko James F. Wilson
author_sort	Nicola Pirastu
title	Author Correction: GWAS for male-pattern baldness identifies 71 susceptibility loci explaining 38% of the risk
title_short	Author Correction: GWAS for male-pattern baldness identifies 71 susceptibility loci explaining 38% of the risk
title_full	Author Correction: GWAS for male-pattern baldness identifies 71 susceptibility loci explaining 38% of the risk
title_fullStr	Author Correction: GWAS for male-pattern baldness identifies 71 susceptibility loci explaining 38% of the risk
title_full_unstemmed	Author Correction: GWAS for male-pattern baldness identifies 71 susceptibility loci explaining 38% of the risk
title_sort	author correction: gwas for male-pattern baldness identifies 71 susceptibility loci explaining 38% of the risk
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/57f23b9d9dec4010aaabffaaa41ec2ed
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Author Correction: GWAS for male-pattern baldness identifies 71 susceptibility loci explaining 38% of the risk

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