Dopamine Is a Siderophore-Like Iron Chelator That Promotes <italic toggle="yes">Salmonella enterica</italic> Serovar Typhimurium Virulence in Mice

Dopamine Is a Siderophore-Like Iron Chelator That Promotes <italic toggle="yes">Salmonella enterica</italic> Serovar Typhimurium Virulence in Mice

ABSTRACT We have recently shown that the catecholamine dopamine regulates cellular iron homeostasis in macrophages. As iron is an essential nutrient for microbes, and intracellular iron availability affects the growth of intracellular bacteria, we studied whether dopamine administration impacts the...

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Autores principales: Stefanie Dichtl, Egon Demetz, David Haschka, Piotr Tymoszuk, Verena Petzer, Manfred Nairz, Markus Seifert, Alexander Hoffmann, Natascha Brigo, Reinhard Würzner, Igor Theurl, Joyce E. Karlinsey, Ferric C. Fang, Günter Weiss
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2019
Materias:
Salmonella Typhimurium
catecholamine
dopamine
iron
qseC
sepsis
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/57f584f7f41d47c996f27ad5c95554b5
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