Cuprizone feed formulation influences the extent of demyelinating disease pathology
Abstract Cuprizone is a copper-chelating agent that induces pathology similar to that within some multiple sclerosis (MS) lesions. The reliability and reproducibility of cuprizone for inducing demyelinating disease pathology depends on the animals ingesting consistent doses of cuprizone. Cuprizone-c...
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Autores principales: | Lillian M. Toomey, Melissa Papini, Brittney Lins, Alexander J. Wright, Andrew Warnock, Terence McGonigle, Sarah C. Hellewell, Carole A. Bartlett, Chidozie Anyaegbu, Melinda Fitzgerald |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/580b3adbc43c41d781115c06f9481e95 |
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