Direct imaging of the circular chromosome in a live bacterium

Bacterial chromosomes are tightly packed, limiting structural analysis by imaging techniques. Here, by quantitative time-lapse single-cell imaging of widened Escherichia coli cells, Wu and Japaridze et al. show that the chromosome exhibits a ring-like torus topology and a dynamic domain structure.

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Autores principales:	Fabai Wu, Aleksandre Japaridze, Xuan Zheng, Jakub Wiktor, Jacob W. J. Kerssemakers, Cees Dekker
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/5820c2a17604433989895a5623404756
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spelling	oai:doaj.org-article:5820c2a17604433989895a56234047562021-12-02T15:35:27ZDirect imaging of the circular chromosome in a live bacterium10.1038/s41467-019-10221-02041-1723https://doaj.org/article/5820c2a17604433989895a56234047562019-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10221-0https://doaj.org/toc/2041-1723Bacterial chromosomes are tightly packed, limiting structural analysis by imaging techniques. Here, by quantitative time-lapse single-cell imaging of widened Escherichia coli cells, Wu and Japaridze et al. show that the chromosome exhibits a ring-like torus topology and a dynamic domain structure.Fabai WuAleksandre JaparidzeXuan ZhengJakub WiktorJacob W. J. KerssemakersCees DekkerNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Fabai Wu Aleksandre Japaridze Xuan Zheng Jakub Wiktor Jacob W. J. Kerssemakers Cees Dekker Direct imaging of the circular chromosome in a live bacterium
description	Bacterial chromosomes are tightly packed, limiting structural analysis by imaging techniques. Here, by quantitative time-lapse single-cell imaging of widened Escherichia coli cells, Wu and Japaridze et al. show that the chromosome exhibits a ring-like torus topology and a dynamic domain structure.
format	article
author	Fabai Wu Aleksandre Japaridze Xuan Zheng Jakub Wiktor Jacob W. J. Kerssemakers Cees Dekker
author_facet	Fabai Wu Aleksandre Japaridze Xuan Zheng Jakub Wiktor Jacob W. J. Kerssemakers Cees Dekker
author_sort	Fabai Wu
title	Direct imaging of the circular chromosome in a live bacterium
title_short	Direct imaging of the circular chromosome in a live bacterium
title_full	Direct imaging of the circular chromosome in a live bacterium
title_fullStr	Direct imaging of the circular chromosome in a live bacterium
title_full_unstemmed	Direct imaging of the circular chromosome in a live bacterium
title_sort	direct imaging of the circular chromosome in a live bacterium
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/5820c2a17604433989895a5623404756
work_keys_str_mv	AT fabaiwu directimagingofthecircularchromosomeinalivebacterium AT aleksandrejaparidze directimagingofthecircularchromosomeinalivebacterium AT xuanzheng directimagingofthecircularchromosomeinalivebacterium AT jakubwiktor directimagingofthecircularchromosomeinalivebacterium AT jacobwjkerssemakers directimagingofthecircularchromosomeinalivebacterium AT ceesdekker directimagingofthecircularchromosomeinalivebacterium
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Direct imaging of the circular chromosome in a live bacterium

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