Discovering genetic interactions bridging pathways in genome-wide association studies

Discovering genetic interactions bridging pathways in genome-wide association studies

Genetic interactions may contribute to phenotypic traits but are challenging to decipher. Here, the authors develop BridGE, a computational approach for identifying pathways connected by genetic interactions from GWAS data.

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Bibliographic Details
Main Authors: Gang Fang, Wen Wang, Vanja Paunic, Hamed Heydari, Michael Costanzo, Xiaoye Liu, Xiaotong Liu, Benjamin VanderSluis, Benjamin Oately, Michael Steinbach, Brian Van Ness, Eric E. Schadt, Nathan D. Pankratz, Charles Boone, Vipin Kumar, Chad L. Myers
Format: article
Language:EN
Published: Nature Portfolio 2019
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Science
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Online Access:https://doaj.org/article/5820ce4d5cb54b95a38d7f821ba26707
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https://doaj.org/article/5820ce4d5cb54b95a38d7f821ba26707

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