Prevalence of adherence to cardiovascular drugs in outpatients with coronary artery disease

Objectives: To describe the prevalence of adherence to drug treatment and the association with sociodemographic, clinical and pharmacotherapeutic factors, in patients diagnosed with coronary artery disease, seen at a multiprofessional cardiology clinic in a public hospital in Belo Horizonte, Minas...

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Autores principales: Maria M. CRUZEIRO, Ronara S. GROIA-VELOSO, Bianca M. DIAS, Adriano M. REIS
Formato: article
Lenguaje:EN
PT
Publicado: Sociedade Brasileira de Farmácia Hospitalar e Serviços de Saúde 2020
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Acceso en línea:https://doaj.org/article/582fbf7a39244e5da07a282c72525e07
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spelling oai:doaj.org-article:582fbf7a39244e5da07a282c72525e072021-11-28T02:44:52ZPrevalence of adherence to cardiovascular drugs in outpatients with coronary artery disease10.30968/rbfhss.2020.112.04592179-59242316-7750https://doaj.org/article/582fbf7a39244e5da07a282c72525e072020-08-01T00:00:00Zhttps://www.rbfhss.org.br/sbrafh/article/view/459https://doaj.org/toc/2179-5924https://doaj.org/toc/2316-7750 Objectives: To describe the prevalence of adherence to drug treatment and the association with sociodemographic, clinical and pharmacotherapeutic factors, in patients diagnosed with coronary artery disease, seen at a multiprofessional cardiology clinic in a public hospital in Belo Horizonte, Minas Gerais. Methods: This is a cross-sectional study conducted between April 2018 and February 2019 in a multiprofessional outpatient cardiology clinic at a teaching hospital. The dependent variable is adherence to treatment with cardiovascular drugs measured by self-report using the 7-day recall and the independent variables evaluated were the sociodemographic, clinical and pharmacotherapeutic variables. Descriptive analysis was performed using frequency distributions for categorical variables and measures of central tendency and dispersion for continuous variables. The association between treatment adherence and independent variables was performed using bivariate analysis using Pearson's chi-square test and the magnitude of the association was expressed by the odds ratio with a 95% confidence interval. Results: 148 patients with a median age of 62 years (IQR = 17.0), mostly male (104; 70.3%) and a median of four years of education (IQR = 4.0). The most prevalent cardiovascular diagnosis was ST-segment elevation acute myocardial infarction (58.8%), followed by non-ST-segment elevation acute myocardial infarction (26.4%) and arrhythmia (23.7%). The most frequent comorbidities were hypertension (72.3%) and diabetes (33.1%). Beta-blockers 98.1% (n = 130) and renin-angiotensin system agents 68.3% (n = 101) were the most commonly used cardiovascular drug classes. No statistically significant association was identified between adherence and sociodemographic, clinical and pharmacotherapeutic factors. Conclusion: The frequency of adherence to treatment measured by 7-days recall was high. Maria M. CRUZEIRORonara S. GROIA-VELOSOBianca M. DIASAdriano M. REISSociedade Brasileira de Farmácia Hospitalar e Serviços de SaúdearticlePublic aspects of medicineRA1-1270Pharmacy and materia medicaRS1-441Therapeutics. PharmacologyRM1-950ENPTRevista Brasileira de Farmácia Hospitalar e Serviços de Saúde, Vol 11, Iss 2 (2020)
institution DOAJ
collection DOAJ
language EN
PT
topic Public aspects of medicine
RA1-1270
Pharmacy and materia medica
RS1-441
Therapeutics. Pharmacology
RM1-950
spellingShingle Public aspects of medicine
RA1-1270
Pharmacy and materia medica
RS1-441
Therapeutics. Pharmacology
RM1-950
Maria M. CRUZEIRO
Ronara S. GROIA-VELOSO
Bianca M. DIAS
Adriano M. REIS
Prevalence of adherence to cardiovascular drugs in outpatients with coronary artery disease
description Objectives: To describe the prevalence of adherence to drug treatment and the association with sociodemographic, clinical and pharmacotherapeutic factors, in patients diagnosed with coronary artery disease, seen at a multiprofessional cardiology clinic in a public hospital in Belo Horizonte, Minas Gerais. Methods: This is a cross-sectional study conducted between April 2018 and February 2019 in a multiprofessional outpatient cardiology clinic at a teaching hospital. The dependent variable is adherence to treatment with cardiovascular drugs measured by self-report using the 7-day recall and the independent variables evaluated were the sociodemographic, clinical and pharmacotherapeutic variables. Descriptive analysis was performed using frequency distributions for categorical variables and measures of central tendency and dispersion for continuous variables. The association between treatment adherence and independent variables was performed using bivariate analysis using Pearson's chi-square test and the magnitude of the association was expressed by the odds ratio with a 95% confidence interval. Results: 148 patients with a median age of 62 years (IQR = 17.0), mostly male (104; 70.3%) and a median of four years of education (IQR = 4.0). The most prevalent cardiovascular diagnosis was ST-segment elevation acute myocardial infarction (58.8%), followed by non-ST-segment elevation acute myocardial infarction (26.4%) and arrhythmia (23.7%). The most frequent comorbidities were hypertension (72.3%) and diabetes (33.1%). Beta-blockers 98.1% (n = 130) and renin-angiotensin system agents 68.3% (n = 101) were the most commonly used cardiovascular drug classes. No statistically significant association was identified between adherence and sociodemographic, clinical and pharmacotherapeutic factors. Conclusion: The frequency of adherence to treatment measured by 7-days recall was high.
format article
author Maria M. CRUZEIRO
Ronara S. GROIA-VELOSO
Bianca M. DIAS
Adriano M. REIS
author_facet Maria M. CRUZEIRO
Ronara S. GROIA-VELOSO
Bianca M. DIAS
Adriano M. REIS
author_sort Maria M. CRUZEIRO
title Prevalence of adherence to cardiovascular drugs in outpatients with coronary artery disease
title_short Prevalence of adherence to cardiovascular drugs in outpatients with coronary artery disease
title_full Prevalence of adherence to cardiovascular drugs in outpatients with coronary artery disease
title_fullStr Prevalence of adherence to cardiovascular drugs in outpatients with coronary artery disease
title_full_unstemmed Prevalence of adherence to cardiovascular drugs in outpatients with coronary artery disease
title_sort prevalence of adherence to cardiovascular drugs in outpatients with coronary artery disease
publisher Sociedade Brasileira de Farmácia Hospitalar e Serviços de Saúde
publishDate 2020
url https://doaj.org/article/582fbf7a39244e5da07a282c72525e07
work_keys_str_mv AT mariamcruzeiro prevalenceofadherencetocardiovasculardrugsinoutpatientswithcoronaryarterydisease
AT ronarasgroiaveloso prevalenceofadherencetocardiovasculardrugsinoutpatientswithcoronaryarterydisease
AT biancamdias prevalenceofadherencetocardiovasculardrugsinoutpatientswithcoronaryarterydisease
AT adrianomreis prevalenceofadherencetocardiovasculardrugsinoutpatientswithcoronaryarterydisease
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