Lectins offer new perspectives in the development of macrophage-targeted therapies for COPD/emphysema.

Lectins offer new perspectives in the development of macrophage-targeted therapies for COPD/emphysema.

We have previously shown that the defective ability of alveolar macrophages (AM) to phagocytose apoptotic cells ('efferocytosis') in chronic obstructive pulmonary disease/emphysema (COPD) could be therapeutically improved using the C-type lectin, mannose binding lectin (MBL), although the...

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Autores principales: Violet R Mukaro, Johan Bylund, Greg Hodge, Mark Holmes, Hubertus Jersmann, Paul N Reynolds, Sandra Hodge
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/58442b7977224fb8ac2766c1c3df0349
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