COMPARASION OF SERUM HOMOCYSTEINE LEVELS IN PRIMIGRAVIDAS DURING SECOND AND THIRD TRIMESTERS OF NORMAL PREGNANCY AND PREECLAMPSIA

Objective: To determine and compare serum homocysteine (Hcy) levels in primigravidas in second and third trimesters of normal pregnancy and preeclampsia. Study Design: Cross-sectional comparative study. Place and Duration of Study: Study was conducted at department of Gynecology and Obstetrics,...

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Autores principales: Alruba Taimoor, Khalid Buland, Aamir Nazir, Sadaf Anwar Qureshi
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Lenguaje:EN
Publicado: Army Medical College Rawalpindi 2019
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spelling oai:doaj.org-article:585bc64eba1046438d5cad3a6cefe8432021-11-12T06:28:04ZCOMPARASION OF SERUM HOMOCYSTEINE LEVELS IN PRIMIGRAVIDAS DURING SECOND AND THIRD TRIMESTERS OF NORMAL PREGNANCY AND PREECLAMPSIA0030-96482411-8842https://doaj.org/article/585bc64eba1046438d5cad3a6cefe8432019-04-01T00:00:00Zhttps://www.pafmj.org/index.php/PAFMJ/article/view/2742/2149https://doaj.org/toc/0030-9648https://doaj.org/toc/2411-8842Objective: To determine and compare serum homocysteine (Hcy) levels in primigravidas in second and third trimesters of normal pregnancy and preeclampsia. Study Design: Cross-sectional comparative study. Place and Duration of Study: Study was conducted at department of Gynecology and Obstetrics, Lahore General Hospital, from June 2013 to May 2014. Material and Methods: One hundred primigravida patients of normal pregnancy and preeclampsia of second and third trimester were evaluated in terms of parameters including blood pressure and Hcy. The subjects were further subdivided into four groups. Age of patients was ranging from 18 to 40 years. Results: The age of selected hundred subjects ranged from 18 to 40 years, while the mean ± SD age was 25.92 ± 5.56 years. Systolic blood pressure ranged from 100 to 210 mmHg, (mean ± SD 136.3 ± 24.623 mmHg). The recorded diastolic blood pressure ranged from 70 to 130 mmHg, (mean ± SD 87.8 ± 15.736 mmHg). There was a significant difference in Hcy amongst pre-eclamptics and controls of 2nd and 3rd trimesters and also between controls of 2nd and 3rd trimesters and cases of both 2nd and 3rd trimesters (p<0.05). Conclusion: There is a significant increase in serum Hcy levels in both second and third trimesters of pregnancies with preeclampsia as compared to controls.Alruba TaimoorKhalid BulandAamir NazirSadaf Anwar QureshiArmy Medical College RawalpindiarticlehomocysteinepreeclampsiaMedicineRMedicine (General)R5-920ENPakistan Armed Forces Medical Journal, Vol 69, Iss 2, Pp 302-306 (2019)
institution DOAJ
collection DOAJ
language EN
topic homocysteine
preeclampsia
Medicine
R
Medicine (General)
R5-920
spellingShingle homocysteine
preeclampsia
Medicine
R
Medicine (General)
R5-920
Alruba Taimoor
Khalid Buland
Aamir Nazir
Sadaf Anwar Qureshi
COMPARASION OF SERUM HOMOCYSTEINE LEVELS IN PRIMIGRAVIDAS DURING SECOND AND THIRD TRIMESTERS OF NORMAL PREGNANCY AND PREECLAMPSIA
description Objective: To determine and compare serum homocysteine (Hcy) levels in primigravidas in second and third trimesters of normal pregnancy and preeclampsia. Study Design: Cross-sectional comparative study. Place and Duration of Study: Study was conducted at department of Gynecology and Obstetrics, Lahore General Hospital, from June 2013 to May 2014. Material and Methods: One hundred primigravida patients of normal pregnancy and preeclampsia of second and third trimester were evaluated in terms of parameters including blood pressure and Hcy. The subjects were further subdivided into four groups. Age of patients was ranging from 18 to 40 years. Results: The age of selected hundred subjects ranged from 18 to 40 years, while the mean ± SD age was 25.92 ± 5.56 years. Systolic blood pressure ranged from 100 to 210 mmHg, (mean ± SD 136.3 ± 24.623 mmHg). The recorded diastolic blood pressure ranged from 70 to 130 mmHg, (mean ± SD 87.8 ± 15.736 mmHg). There was a significant difference in Hcy amongst pre-eclamptics and controls of 2nd and 3rd trimesters and also between controls of 2nd and 3rd trimesters and cases of both 2nd and 3rd trimesters (p<0.05). Conclusion: There is a significant increase in serum Hcy levels in both second and third trimesters of pregnancies with preeclampsia as compared to controls.
format article
author Alruba Taimoor
Khalid Buland
Aamir Nazir
Sadaf Anwar Qureshi
author_facet Alruba Taimoor
Khalid Buland
Aamir Nazir
Sadaf Anwar Qureshi
author_sort Alruba Taimoor
title COMPARASION OF SERUM HOMOCYSTEINE LEVELS IN PRIMIGRAVIDAS DURING SECOND AND THIRD TRIMESTERS OF NORMAL PREGNANCY AND PREECLAMPSIA
title_short COMPARASION OF SERUM HOMOCYSTEINE LEVELS IN PRIMIGRAVIDAS DURING SECOND AND THIRD TRIMESTERS OF NORMAL PREGNANCY AND PREECLAMPSIA
title_full COMPARASION OF SERUM HOMOCYSTEINE LEVELS IN PRIMIGRAVIDAS DURING SECOND AND THIRD TRIMESTERS OF NORMAL PREGNANCY AND PREECLAMPSIA
title_fullStr COMPARASION OF SERUM HOMOCYSTEINE LEVELS IN PRIMIGRAVIDAS DURING SECOND AND THIRD TRIMESTERS OF NORMAL PREGNANCY AND PREECLAMPSIA
title_full_unstemmed COMPARASION OF SERUM HOMOCYSTEINE LEVELS IN PRIMIGRAVIDAS DURING SECOND AND THIRD TRIMESTERS OF NORMAL PREGNANCY AND PREECLAMPSIA
title_sort comparasion of serum homocysteine levels in primigravidas during second and third trimesters of normal pregnancy and preeclampsia
publisher Army Medical College Rawalpindi
publishDate 2019
url https://doaj.org/article/585bc64eba1046438d5cad3a6cefe843
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AT aamirnazir comparasionofserumhomocysteinelevelsinprimigravidasduringsecondandthirdtrimestersofnormalpregnancyandpreeclampsia
AT sadafanwarqureshi comparasionofserumhomocysteinelevelsinprimigravidasduringsecondandthirdtrimestersofnormalpregnancyandpreeclampsia
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