Generation of a more efficient prime editor 2 by addition of the Rad51 DNA-binding domain

Generation of a more efficient prime editor 2 by addition of the Rad51 DNA-binding domain

While prime editing is a promising technology, PE2 systems often have low efficiency. Here the authors fuse a Rad51 DNA-binding domain to create hyPE2 with improved editing efficiency.

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Detalles Bibliográficos
Autores principales: Myungjae Song, Jung Min Lim, Seonwoo Min, Jeong-Seok Oh, Dong Young Kim, Jae-Sung Woo, Hiroshi Nishimasu, Sung-Rae Cho, Sungroh Yoon, Hyongbum Henry Kim
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Science
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Acceso en línea:https://doaj.org/article/585d27be31a74bf5926e523fa4034081
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