The Evolution of Very Early Onset Inflammatory Bowel Disease, Autoimmune Hepatitis, and Primary Sclerosing Cholangitis in a Young Girl

Very early onset inflammatory bowel disease, autoimmune hepatitis (AIH), or primary sclerosing cholangitis (PSC) alone is a rare condition in young children. The combination of all 3 autoimmune disorders in a 16-month-old child is even rarer. The onset and etiology of these diseases is multifactoria...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Aditi Dey, Jacquelin Peck, Michael Wilsey, Jolan Walter, Johnny Nguyen, Ignacio Gonzalez-Gomez, Sara Karjoo
Formato:	article
Lenguaje:	EN
Publicado:	Karger Publishers 2021
Materias:	autoimmune hepatitis crohn’s disease very early onset inflammatory bowel disease primary sclerosing cholangitis Diseases of the digestive system. Gastroenterology RC799-869
Acceso en línea:	https://doaj.org/article/586271e2078b4b38b2073e898bf78239
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:586271e2078b4b38b2073e898bf78239
record_format	dspace
spelling	oai:doaj.org-article:586271e2078b4b38b2073e898bf782392021-12-02T12:40:22ZThe Evolution of Very Early Onset Inflammatory Bowel Disease, Autoimmune Hepatitis, and Primary Sclerosing Cholangitis in a Young Girl1662-063110.1159/000520184https://doaj.org/article/586271e2078b4b38b2073e898bf782392021-11-01T00:00:00Zhttps://www.karger.com/Article/FullText/520184https://doaj.org/toc/1662-0631Very early onset inflammatory bowel disease, autoimmune hepatitis (AIH), or primary sclerosing cholangitis (PSC) alone is a rare condition in young children. The combination of all 3 autoimmune disorders in a 16-month-old child is even rarer. The onset and etiology of these diseases is multifactorial and typically unknown. However, when the children are diagnosed, the accepted view point is that the inflammation was likely present for months to years prior. This case is unique because the gastrointestinal problems started from infancy, and evolved to the development of Crohn’s disease, AIH, and PSC at a very early age. This case helps bring to light that very early onset autoimmune disorders may in fact present with symptoms of feeding difficulties, growth failure, and formula intolerance. Patients may be diagnosed initially with allergic enterocolitis in infancy. Although few children with these symptoms evolve to develop autoimmune diseases at an older age, clinicians should consider following these children more closely. This case also demonstrates how hard it is to diagnose very early onset autoimmune disorders, as they mimic other illnesses.Aditi DeyJacquelin PeckMichael WilseyJolan WalterJohnny NguyenIgnacio Gonzalez-GomezSara KarjooKarger Publishersarticleautoimmune hepatitiscrohn’s diseasevery early onset inflammatory bowel diseaseprimary sclerosing cholangitisDiseases of the digestive system. GastroenterologyRC799-869ENCase Reports in Gastroenterology, Vol 15, Iss 3, Pp 939-947 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	autoimmune hepatitis crohn’s disease very early onset inflammatory bowel disease primary sclerosing cholangitis Diseases of the digestive system. Gastroenterology RC799-869
spellingShingle	autoimmune hepatitis crohn’s disease very early onset inflammatory bowel disease primary sclerosing cholangitis Diseases of the digestive system. Gastroenterology RC799-869 Aditi Dey Jacquelin Peck Michael Wilsey Jolan Walter Johnny Nguyen Ignacio Gonzalez-Gomez Sara Karjoo The Evolution of Very Early Onset Inflammatory Bowel Disease, Autoimmune Hepatitis, and Primary Sclerosing Cholangitis in a Young Girl
description	Very early onset inflammatory bowel disease, autoimmune hepatitis (AIH), or primary sclerosing cholangitis (PSC) alone is a rare condition in young children. The combination of all 3 autoimmune disorders in a 16-month-old child is even rarer. The onset and etiology of these diseases is multifactorial and typically unknown. However, when the children are diagnosed, the accepted view point is that the inflammation was likely present for months to years prior. This case is unique because the gastrointestinal problems started from infancy, and evolved to the development of Crohn’s disease, AIH, and PSC at a very early age. This case helps bring to light that very early onset autoimmune disorders may in fact present with symptoms of feeding difficulties, growth failure, and formula intolerance. Patients may be diagnosed initially with allergic enterocolitis in infancy. Although few children with these symptoms evolve to develop autoimmune diseases at an older age, clinicians should consider following these children more closely. This case also demonstrates how hard it is to diagnose very early onset autoimmune disorders, as they mimic other illnesses.
format	article
author	Aditi Dey Jacquelin Peck Michael Wilsey Jolan Walter Johnny Nguyen Ignacio Gonzalez-Gomez Sara Karjoo
author_facet	Aditi Dey Jacquelin Peck Michael Wilsey Jolan Walter Johnny Nguyen Ignacio Gonzalez-Gomez Sara Karjoo
author_sort	Aditi Dey
title	The Evolution of Very Early Onset Inflammatory Bowel Disease, Autoimmune Hepatitis, and Primary Sclerosing Cholangitis in a Young Girl
title_short	The Evolution of Very Early Onset Inflammatory Bowel Disease, Autoimmune Hepatitis, and Primary Sclerosing Cholangitis in a Young Girl
title_full	The Evolution of Very Early Onset Inflammatory Bowel Disease, Autoimmune Hepatitis, and Primary Sclerosing Cholangitis in a Young Girl
title_fullStr	The Evolution of Very Early Onset Inflammatory Bowel Disease, Autoimmune Hepatitis, and Primary Sclerosing Cholangitis in a Young Girl
title_full_unstemmed	The Evolution of Very Early Onset Inflammatory Bowel Disease, Autoimmune Hepatitis, and Primary Sclerosing Cholangitis in a Young Girl
title_sort	evolution of very early onset inflammatory bowel disease, autoimmune hepatitis, and primary sclerosing cholangitis in a young girl
publisher	Karger Publishers
publishDate	2021
url	https://doaj.org/article/586271e2078b4b38b2073e898bf78239
work_keys_str_mv	AT aditidey theevolutionofveryearlyonsetinflammatoryboweldiseaseautoimmunehepatitisandprimarysclerosingcholangitisinayounggirl AT jacquelinpeck theevolutionofveryearlyonsetinflammatoryboweldiseaseautoimmunehepatitisandprimarysclerosingcholangitisinayounggirl AT michaelwilsey theevolutionofveryearlyonsetinflammatoryboweldiseaseautoimmunehepatitisandprimarysclerosingcholangitisinayounggirl AT jolanwalter theevolutionofveryearlyonsetinflammatoryboweldiseaseautoimmunehepatitisandprimarysclerosingcholangitisinayounggirl AT johnnynguyen theevolutionofveryearlyonsetinflammatoryboweldiseaseautoimmunehepatitisandprimarysclerosingcholangitisinayounggirl AT ignaciogonzalezgomez theevolutionofveryearlyonsetinflammatoryboweldiseaseautoimmunehepatitisandprimarysclerosingcholangitisinayounggirl AT sarakarjoo theevolutionofveryearlyonsetinflammatoryboweldiseaseautoimmunehepatitisandprimarysclerosingcholangitisinayounggirl AT aditidey evolutionofveryearlyonsetinflammatoryboweldiseaseautoimmunehepatitisandprimarysclerosingcholangitisinayounggirl AT jacquelinpeck evolutionofveryearlyonsetinflammatoryboweldiseaseautoimmunehepatitisandprimarysclerosingcholangitisinayounggirl AT michaelwilsey evolutionofveryearlyonsetinflammatoryboweldiseaseautoimmunehepatitisandprimarysclerosingcholangitisinayounggirl AT jolanwalter evolutionofveryearlyonsetinflammatoryboweldiseaseautoimmunehepatitisandprimarysclerosingcholangitisinayounggirl AT johnnynguyen evolutionofveryearlyonsetinflammatoryboweldiseaseautoimmunehepatitisandprimarysclerosingcholangitisinayounggirl AT ignaciogonzalezgomez evolutionofveryearlyonsetinflammatoryboweldiseaseautoimmunehepatitisandprimarysclerosingcholangitisinayounggirl AT sarakarjoo evolutionofveryearlyonsetinflammatoryboweldiseaseautoimmunehepatitisandprimarysclerosingcholangitisinayounggirl
_version_	1718393738908139520

The Evolution of Very Early Onset Inflammatory Bowel Disease, Autoimmune Hepatitis, and Primary Sclerosing Cholangitis in a Young Girl

Ejemplares similares