Composition of nasal bacterial community and its seasonal variation in health care workers stationed in a clinical research laboratory.

The microorganisms at the workplace contribute towards a large portion of the biodiversity a person encounters in his or her life. Health care professionals are often at risk due to their frontline nature of work. Competition and cooperation between nasal bacterial communities of individuals working...

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Autores principales:	Nazima Habibi, Abu Salim Mustafa, Mohd Wasif Khan
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/5864f65724184693a1fa77605d7a4291
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spelling	oai:doaj.org-article:5864f65724184693a1fa77605d7a42912021-12-02T20:16:07ZComposition of nasal bacterial community and its seasonal variation in health care workers stationed in a clinical research laboratory.1932-620310.1371/journal.pone.0260314https://doaj.org/article/5864f65724184693a1fa77605d7a42912021-01-01T00:00:00Zhttps://doi.org/10.1371/journal.pone.0260314https://doaj.org/toc/1932-6203The microorganisms at the workplace contribute towards a large portion of the biodiversity a person encounters in his or her life. Health care professionals are often at risk due to their frontline nature of work. Competition and cooperation between nasal bacterial communities of individuals working in a health care setting have been shown to mediate pathogenic microbes. Therefore, we investigated the nasal bacterial community of 47 healthy individuals working in a clinical research laboratory in Kuwait. The taxonomic profiling and core microbiome analysis identified three pre-dominant genera as Corynebacterium (15.0%), Staphylococcus (10.3%) and, Moraxella (10.0%). All the bacterial genera exhibited seasonal variations in summer, winter, autumn and spring. SparCC correlation network analysis revealed positive and negative correlations among the classified genera. A rich set of 16 genera (q < 0.05) were significantly differentially abundant (LEfSe) across the four seasons. The highest species counts, richness and evenness (P < 0.005) were recorded in autumn. Community structure profiling indicated that the entire bacterial population followed a seasonal distribution (R2-0.371; P < 0.001). Other demographic factors such as age, gender and, ethnicity contributed minimally towards community clustering in a closed indoor laboratory setting. Intra-personal diversity also witnessed rich species variety (maximum 6.8 folds). Seasonal changes in the indoor working place in conjunction with the outdoor atmosphere seems to be important for the variations in the nasal bacterial communities of professionals working in a health care setting.Nazima HabibiAbu Salim MustafaMohd Wasif KhanPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 16, Iss 11, p e0260314 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Nazima Habibi Abu Salim Mustafa Mohd Wasif Khan Composition of nasal bacterial community and its seasonal variation in health care workers stationed in a clinical research laboratory.
description	The microorganisms at the workplace contribute towards a large portion of the biodiversity a person encounters in his or her life. Health care professionals are often at risk due to their frontline nature of work. Competition and cooperation between nasal bacterial communities of individuals working in a health care setting have been shown to mediate pathogenic microbes. Therefore, we investigated the nasal bacterial community of 47 healthy individuals working in a clinical research laboratory in Kuwait. The taxonomic profiling and core microbiome analysis identified three pre-dominant genera as Corynebacterium (15.0%), Staphylococcus (10.3%) and, Moraxella (10.0%). All the bacterial genera exhibited seasonal variations in summer, winter, autumn and spring. SparCC correlation network analysis revealed positive and negative correlations among the classified genera. A rich set of 16 genera (q < 0.05) were significantly differentially abundant (LEfSe) across the four seasons. The highest species counts, richness and evenness (P < 0.005) were recorded in autumn. Community structure profiling indicated that the entire bacterial population followed a seasonal distribution (R2-0.371; P < 0.001). Other demographic factors such as age, gender and, ethnicity contributed minimally towards community clustering in a closed indoor laboratory setting. Intra-personal diversity also witnessed rich species variety (maximum 6.8 folds). Seasonal changes in the indoor working place in conjunction with the outdoor atmosphere seems to be important for the variations in the nasal bacterial communities of professionals working in a health care setting.
format	article
author	Nazima Habibi Abu Salim Mustafa Mohd Wasif Khan
author_facet	Nazima Habibi Abu Salim Mustafa Mohd Wasif Khan
author_sort	Nazima Habibi
title	Composition of nasal bacterial community and its seasonal variation in health care workers stationed in a clinical research laboratory.
title_short	Composition of nasal bacterial community and its seasonal variation in health care workers stationed in a clinical research laboratory.
title_full	Composition of nasal bacterial community and its seasonal variation in health care workers stationed in a clinical research laboratory.
title_fullStr	Composition of nasal bacterial community and its seasonal variation in health care workers stationed in a clinical research laboratory.
title_full_unstemmed	Composition of nasal bacterial community and its seasonal variation in health care workers stationed in a clinical research laboratory.
title_sort	composition of nasal bacterial community and its seasonal variation in health care workers stationed in a clinical research laboratory.
publisher	Public Library of Science (PLoS)
publishDate	2021
url	https://doaj.org/article/5864f65724184693a1fa77605d7a4291
work_keys_str_mv	AT nazimahabibi compositionofnasalbacterialcommunityanditsseasonalvariationinhealthcareworkersstationedinaclinicalresearchlaboratory AT abusalimmustafa compositionofnasalbacterialcommunityanditsseasonalvariationinhealthcareworkersstationedinaclinicalresearchlaboratory AT mohdwasifkhan compositionofnasalbacterialcommunityanditsseasonalvariationinhealthcareworkersstationedinaclinicalresearchlaboratory
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Composition of nasal bacterial community and its seasonal variation in health care workers stationed in a clinical research laboratory.

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