The Application of Exercise Training for Diabetic Peripheral Neuropathy

Diabetic peripheral neuropathy (DPN) is the presence of symptoms and/or signs of peripheral nerve dysfunction in people with diabetes after the exclusion of other causes. It is associated with pain, paresthesia, sensory loss, muscle atrophy with fat infiltration, and muscular dysfunction typically s...

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Autores principales:	Clifton J. Holmes, Mary K. Hastings
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	diabetes mellitus sensorimotor physical training therapy hyperglycemia Medicine R
Acceso en línea:	https://doaj.org/article/58661af0d3ac445285b4b02d75f4ee22
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spelling	oai:doaj.org-article:58661af0d3ac445285b4b02d75f4ee222021-11-11T17:39:47ZThe Application of Exercise Training for Diabetic Peripheral Neuropathy10.3390/jcm102150422077-0383https://doaj.org/article/58661af0d3ac445285b4b02d75f4ee222021-10-01T00:00:00Zhttps://www.mdpi.com/2077-0383/10/21/5042https://doaj.org/toc/2077-0383Diabetic peripheral neuropathy (DPN) is the presence of symptoms and/or signs of peripheral nerve dysfunction in people with diabetes after the exclusion of other causes. It is associated with pain, paresthesia, sensory loss, muscle atrophy with fat infiltration, and muscular dysfunction typically starting distally in the feet and progressing proximally. Muscle deterioration within the leg and foot can lead to muscle dysfunction, reduced mobility, and increases the risk of disability, ulceration, and amputation. Exercise training is an established method for increasing the different components of physical fitness, including enhancing body composition and improving neuromuscular strength. A number of experimental studies have utilized exercise training to treat various impairments associated with DPN, such as nerve conduction velocity, pain tolerance, and balance. However, the broad spectrum of exercise training modalities implemented and differences in target outcome measurements have made it difficult to understand the efficacy of exercise training interventions or provide appropriate exercise prescription recommendations. Therefore, the aims of this review were to (1) briefly describe the pathophysiology of DPN and (2) discuss the effects of exercise training interventions on sensorimotor, metabolic, and physical functions in people with DPN.Clifton J. HolmesMary K. HastingsMDPI AGarticlediabetes mellitussensorimotorphysical trainingtherapyhyperglycemiaMedicineRENJournal of Clinical Medicine, Vol 10, Iss 5042, p 5042 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	diabetes mellitus sensorimotor physical training therapy hyperglycemia Medicine R
spellingShingle	diabetes mellitus sensorimotor physical training therapy hyperglycemia Medicine R Clifton J. Holmes Mary K. Hastings The Application of Exercise Training for Diabetic Peripheral Neuropathy
description	Diabetic peripheral neuropathy (DPN) is the presence of symptoms and/or signs of peripheral nerve dysfunction in people with diabetes after the exclusion of other causes. It is associated with pain, paresthesia, sensory loss, muscle atrophy with fat infiltration, and muscular dysfunction typically starting distally in the feet and progressing proximally. Muscle deterioration within the leg and foot can lead to muscle dysfunction, reduced mobility, and increases the risk of disability, ulceration, and amputation. Exercise training is an established method for increasing the different components of physical fitness, including enhancing body composition and improving neuromuscular strength. A number of experimental studies have utilized exercise training to treat various impairments associated with DPN, such as nerve conduction velocity, pain tolerance, and balance. However, the broad spectrum of exercise training modalities implemented and differences in target outcome measurements have made it difficult to understand the efficacy of exercise training interventions or provide appropriate exercise prescription recommendations. Therefore, the aims of this review were to (1) briefly describe the pathophysiology of DPN and (2) discuss the effects of exercise training interventions on sensorimotor, metabolic, and physical functions in people with DPN.
format	article
author	Clifton J. Holmes Mary K. Hastings
author_facet	Clifton J. Holmes Mary K. Hastings
author_sort	Clifton J. Holmes
title	The Application of Exercise Training for Diabetic Peripheral Neuropathy
title_short	The Application of Exercise Training for Diabetic Peripheral Neuropathy
title_full	The Application of Exercise Training for Diabetic Peripheral Neuropathy
title_fullStr	The Application of Exercise Training for Diabetic Peripheral Neuropathy
title_full_unstemmed	The Application of Exercise Training for Diabetic Peripheral Neuropathy
title_sort	application of exercise training for diabetic peripheral neuropathy
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/58661af0d3ac445285b4b02d75f4ee22
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The Application of Exercise Training for Diabetic Peripheral Neuropathy

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