Glioblastoma cell-secreted interleukin-8 induces brain endothelial cell permeability via CXCR2.

Glioblastoma constitutes the most aggressive and deadly of brain tumors. As yet, both conventional and molecular-based therapies have met with limited success in treatment of this cancer. Among other explanations, the heterogeneity of glioblastoma and the associated microenvironment contribute to it...

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Autores principales: Julie Dwyer, Jagoda K Hebda, Armelle Le Guelte, Eva-Maria Galan-Moya, Sherri S Smith, Sandy Azzi, Nicolas Bidere, Julie Gavard
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/586ebc2991014042904bb799e4964e01
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