ELAVL1a is an immunocompetent protein that protects zebrafish embryos from bacterial infection

Ni et al. show that RNA-binding protein ELAVL1a is abundantly stored in the eggs and embryos of zebrafish, serving as a first-line innate immune player. They find that ELAVL1a recognizes molecular patterns of bacteria to inhibit bacterial growth. This study suggests that ELAVL1a is a maternal immune...

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Main Authors: Shousheng Ni, Yang Zhou, Lili Song, Yan Chen, Xia Wang, Xiaoyuan Du, Shicui Zhang
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Online Access:https://doaj.org/article/5881436e29ab4d76bbdf71d8d7a7fa24
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spelling oai:doaj.org-article:5881436e29ab4d76bbdf71d8d7a7fa242021-12-02T13:19:20ZELAVL1a is an immunocompetent protein that protects zebrafish embryos from bacterial infection10.1038/s42003-021-01777-z2399-3642https://doaj.org/article/5881436e29ab4d76bbdf71d8d7a7fa242021-02-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-01777-zhttps://doaj.org/toc/2399-3642Ni et al. show that RNA-binding protein ELAVL1a is abundantly stored in the eggs and embryos of zebrafish, serving as a first-line innate immune player. They find that ELAVL1a recognizes molecular patterns of bacteria to inhibit bacterial growth. This study suggests that ELAVL1a is a maternal immune factor protecting zebrafish embryos from bacterial infection.Shousheng NiYang ZhouLili SongYan ChenXia WangXiaoyuan DuShicui ZhangNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
institution DOAJ
collection DOAJ
language EN
topic Biology (General)
QH301-705.5
spellingShingle Biology (General)
QH301-705.5
Shousheng Ni
Yang Zhou
Lili Song
Yan Chen
Xia Wang
Xiaoyuan Du
Shicui Zhang
ELAVL1a is an immunocompetent protein that protects zebrafish embryos from bacterial infection
description Ni et al. show that RNA-binding protein ELAVL1a is abundantly stored in the eggs and embryos of zebrafish, serving as a first-line innate immune player. They find that ELAVL1a recognizes molecular patterns of bacteria to inhibit bacterial growth. This study suggests that ELAVL1a is a maternal immune factor protecting zebrafish embryos from bacterial infection.
format article
author Shousheng Ni
Yang Zhou
Lili Song
Yan Chen
Xia Wang
Xiaoyuan Du
Shicui Zhang
author_facet Shousheng Ni
Yang Zhou
Lili Song
Yan Chen
Xia Wang
Xiaoyuan Du
Shicui Zhang
author_sort Shousheng Ni
title ELAVL1a is an immunocompetent protein that protects zebrafish embryos from bacterial infection
title_short ELAVL1a is an immunocompetent protein that protects zebrafish embryos from bacterial infection
title_full ELAVL1a is an immunocompetent protein that protects zebrafish embryos from bacterial infection
title_fullStr ELAVL1a is an immunocompetent protein that protects zebrafish embryos from bacterial infection
title_full_unstemmed ELAVL1a is an immunocompetent protein that protects zebrafish embryos from bacterial infection
title_sort elavl1a is an immunocompetent protein that protects zebrafish embryos from bacterial infection
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/5881436e29ab4d76bbdf71d8d7a7fa24
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