Toll-like receptor 4 promoter polymorphisms: common TLR4 variants may protect against severe urinary tract infection.

Toll-like receptor 4 promoter polymorphisms: common TLR4 variants may protect against severe urinary tract infection.

<h4>Background</h4>Polymorphisms affecting Toll-like receptor (TLR) structure appear to be rare, as would be expected due to their essential coordinator role in innate immunity. Here, we assess variation in TLR4 expression, rather than structure, as a mechanism to diversify innate immune...

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Autores principales: Bryndís Ragnarsdóttir, Klas Jönsson, Alexander Urbano, Jenny Grönberg-Hernandez, Nataliya Lutay, Martti Tammi, Mattias Gustafsson, Ann-Charlotte Lundstedt, Irene Leijonhufvud, Diana Karpman, Björn Wullt, Lennart Truedsson, Ulf Jodal, Björn Andersson, Catharina Svanborg
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2010
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/588838fafd4343628d0638680e63bd0e
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