Mir-132/212 is required for maturation of binocular matching of orientation preference and depth perception
miR-132/212 has been implicated in ocular dominance plasticity during the critical period. Here the authors show that miR-132/212 regulates the expression of genes involved in visual cortex maturation, and that mice lack miR-132/212 show deficits in binocular matching of orientation preferences, whi...
Guardado en:
Autores principales: | , , , , , , , , , , , , , |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
|
Materias: | |
Acceso en línea: | https://doaj.org/article/5888fc985dda4b93a052f3e04b218072 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
id |
oai:doaj.org-article:5888fc985dda4b93a052f3e04b218072 |
---|---|
record_format |
dspace |
spelling |
oai:doaj.org-article:5888fc985dda4b93a052f3e04b2180722021-12-02T14:42:45ZMir-132/212 is required for maturation of binocular matching of orientation preference and depth perception10.1038/ncomms154882041-1723https://doaj.org/article/5888fc985dda4b93a052f3e04b2180722017-05-01T00:00:00Zhttps://doi.org/10.1038/ncomms15488https://doaj.org/toc/2041-1723miR-132/212 has been implicated in ocular dominance plasticity during the critical period. Here the authors show that miR-132/212 regulates the expression of genes involved in visual cortex maturation, and that mice lack miR-132/212 show deficits in binocular matching of orientation preferences, which leads to impaired depth perception.Raffaele MazziottiLaura BaroncelliNicholas CegliaGabriele CheliniGrazia Della SalaChristophe MagnanDebora NapoliElena PutignanoDavide SilingardiJonida TolaPaola TogniniJ. Simon C. ArthurPierre BaldiTommaso PizzorussoNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-12 (2017) |
institution |
DOAJ |
collection |
DOAJ |
language |
EN |
topic |
Science Q |
spellingShingle |
Science Q Raffaele Mazziotti Laura Baroncelli Nicholas Ceglia Gabriele Chelini Grazia Della Sala Christophe Magnan Debora Napoli Elena Putignano Davide Silingardi Jonida Tola Paola Tognini J. Simon C. Arthur Pierre Baldi Tommaso Pizzorusso Mir-132/212 is required for maturation of binocular matching of orientation preference and depth perception |
description |
miR-132/212 has been implicated in ocular dominance plasticity during the critical period. Here the authors show that miR-132/212 regulates the expression of genes involved in visual cortex maturation, and that mice lack miR-132/212 show deficits in binocular matching of orientation preferences, which leads to impaired depth perception. |
format |
article |
author |
Raffaele Mazziotti Laura Baroncelli Nicholas Ceglia Gabriele Chelini Grazia Della Sala Christophe Magnan Debora Napoli Elena Putignano Davide Silingardi Jonida Tola Paola Tognini J. Simon C. Arthur Pierre Baldi Tommaso Pizzorusso |
author_facet |
Raffaele Mazziotti Laura Baroncelli Nicholas Ceglia Gabriele Chelini Grazia Della Sala Christophe Magnan Debora Napoli Elena Putignano Davide Silingardi Jonida Tola Paola Tognini J. Simon C. Arthur Pierre Baldi Tommaso Pizzorusso |
author_sort |
Raffaele Mazziotti |
title |
Mir-132/212 is required for maturation of binocular matching of orientation preference and depth perception |
title_short |
Mir-132/212 is required for maturation of binocular matching of orientation preference and depth perception |
title_full |
Mir-132/212 is required for maturation of binocular matching of orientation preference and depth perception |
title_fullStr |
Mir-132/212 is required for maturation of binocular matching of orientation preference and depth perception |
title_full_unstemmed |
Mir-132/212 is required for maturation of binocular matching of orientation preference and depth perception |
title_sort |
mir-132/212 is required for maturation of binocular matching of orientation preference and depth perception |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/5888fc985dda4b93a052f3e04b218072 |
work_keys_str_mv |
AT raffaelemazziotti mir132212isrequiredformaturationofbinocularmatchingoforientationpreferenceanddepthperception AT laurabaroncelli mir132212isrequiredformaturationofbinocularmatchingoforientationpreferenceanddepthperception AT nicholasceglia mir132212isrequiredformaturationofbinocularmatchingoforientationpreferenceanddepthperception AT gabrielechelini mir132212isrequiredformaturationofbinocularmatchingoforientationpreferenceanddepthperception AT graziadellasala mir132212isrequiredformaturationofbinocularmatchingoforientationpreferenceanddepthperception AT christophemagnan mir132212isrequiredformaturationofbinocularmatchingoforientationpreferenceanddepthperception AT deboranapoli mir132212isrequiredformaturationofbinocularmatchingoforientationpreferenceanddepthperception AT elenaputignano mir132212isrequiredformaturationofbinocularmatchingoforientationpreferenceanddepthperception AT davidesilingardi mir132212isrequiredformaturationofbinocularmatchingoforientationpreferenceanddepthperception AT jonidatola mir132212isrequiredformaturationofbinocularmatchingoforientationpreferenceanddepthperception AT paolatognini mir132212isrequiredformaturationofbinocularmatchingoforientationpreferenceanddepthperception AT jsimoncarthur mir132212isrequiredformaturationofbinocularmatchingoforientationpreferenceanddepthperception AT pierrebaldi mir132212isrequiredformaturationofbinocularmatchingoforientationpreferenceanddepthperception AT tommasopizzorusso mir132212isrequiredformaturationofbinocularmatchingoforientationpreferenceanddepthperception |
_version_ |
1718389568906985472 |