Femtosecond Laser-Assisted Big-Bubble Deep Anterior Lamellar Keratoplasty

Emilio Pedrotti,1 Erika Bonacci,1 Arianna De Rossi,1 Jacopo Bonetto,1 Chiara Chierego,1 Adriano Fasolo,1,2 Alessandra De Gregorio,3 Giorgio Marchini1 1Ophthalmic Unit, Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Policlinico G.B. Rossi, Verona, 37134, Italy;...

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Autores principales: Pedrotti E, Bonacci E, De Rossi A, Bonetto J, Chierego C, Fasolo A, De Gregorio A, Marchini G
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Lenguaje:EN
Publicado: Dove Medical Press 2021
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spelling oai:doaj.org-article:588f650cf96d4eec9daaf33f5cd7804d2021-12-02T14:12:25ZFemtosecond Laser-Assisted Big-Bubble Deep Anterior Lamellar Keratoplasty1177-5483https://doaj.org/article/588f650cf96d4eec9daaf33f5cd7804d2021-02-01T00:00:00Zhttps://www.dovepress.com/femtosecond-laser-assisted-big-bubble-deep-anterior-lamellar-keratopla-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Emilio Pedrotti,1 Erika Bonacci,1 Arianna De Rossi,1 Jacopo Bonetto,1 Chiara Chierego,1 Adriano Fasolo,1,2 Alessandra De Gregorio,3 Giorgio Marchini1 1Ophthalmic Unit, Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Policlinico G.B. Rossi, Verona, 37134, Italy; 2Research Unit, The Veneto Eye Bank Foundation, Venezia, 30174, Italy; 3Ophthalmic Unit, San Bassiano Hospital, Bassano Del Grappa, 36061, Vicenza, ItalyCorrespondence: Adriano FasoloThe Veneto Eye Bank Foundation, c/o Pad. G. Rama, via Paccagnella 11, Venice, 30174, ItalyTel +390419656400Fax +390419656401Email adriano.fasolo@yahoo.itPurpose: To determine whether type 1 big-bubble (BB) formation is influenced by the sequence of incisions created with the Victus femtosecond laser (FSL) enabled with software version 3.4 (SV 3.4) during deep anterior lamellar keratoplasty (DALK).Materials and Methods: Consecutive FSL-assisted DALK BB procedures were performed on 20 human donor corneas: 10 shaped by tunnel incision followed by lamellar incision (tunnel-lamellar group, TL) and 10 in the reverse order (lamellar-tunnel group, LT). The BB type was assessed by evaluating dynamic air movement during air inflation; bubble diameter and floor thickness were measured by anterior segment optical coherence tomography.Results: Overall, a type 1 BB formed in 85% of eyes: 100% in the TL group and 70% in the LT group. In the LT group, a type 2 BB formed in 2 corneas and one cornea was perforated during cannula insertion. Type 1 BB was achieved after one attempt in 90% of eyes in the TL group and in 57% in the LT group.Conclusion: Shaping the tunnel before rather than after lamellar incision may be more effective for obtaining a type 1 BB by air injection.Keywords: deep anterior lamellar keratoplasty, femtosecond laser, big bubble, intrastromal incision, lamellar incisionPedrotti EBonacci EDe Rossi ABonetto JChierego CFasolo ADe Gregorio AMarchini GDove Medical Pressarticledeep anterior lamellar keratoplastyfemtosecond laserbig bubbleintrastromal incisionlamellar incisionOphthalmologyRE1-994ENClinical Ophthalmology, Vol Volume 15, Pp 645-650 (2021)
institution DOAJ
collection DOAJ
language EN
topic deep anterior lamellar keratoplasty
femtosecond laser
big bubble
intrastromal incision
lamellar incision
Ophthalmology
RE1-994
spellingShingle deep anterior lamellar keratoplasty
femtosecond laser
big bubble
intrastromal incision
lamellar incision
Ophthalmology
RE1-994
Pedrotti E
Bonacci E
De Rossi A
Bonetto J
Chierego C
Fasolo A
De Gregorio A
Marchini G
Femtosecond Laser-Assisted Big-Bubble Deep Anterior Lamellar Keratoplasty
description Emilio Pedrotti,1 Erika Bonacci,1 Arianna De Rossi,1 Jacopo Bonetto,1 Chiara Chierego,1 Adriano Fasolo,1,2 Alessandra De Gregorio,3 Giorgio Marchini1 1Ophthalmic Unit, Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Policlinico G.B. Rossi, Verona, 37134, Italy; 2Research Unit, The Veneto Eye Bank Foundation, Venezia, 30174, Italy; 3Ophthalmic Unit, San Bassiano Hospital, Bassano Del Grappa, 36061, Vicenza, ItalyCorrespondence: Adriano FasoloThe Veneto Eye Bank Foundation, c/o Pad. G. Rama, via Paccagnella 11, Venice, 30174, ItalyTel +390419656400Fax +390419656401Email adriano.fasolo@yahoo.itPurpose: To determine whether type 1 big-bubble (BB) formation is influenced by the sequence of incisions created with the Victus femtosecond laser (FSL) enabled with software version 3.4 (SV 3.4) during deep anterior lamellar keratoplasty (DALK).Materials and Methods: Consecutive FSL-assisted DALK BB procedures were performed on 20 human donor corneas: 10 shaped by tunnel incision followed by lamellar incision (tunnel-lamellar group, TL) and 10 in the reverse order (lamellar-tunnel group, LT). The BB type was assessed by evaluating dynamic air movement during air inflation; bubble diameter and floor thickness were measured by anterior segment optical coherence tomography.Results: Overall, a type 1 BB formed in 85% of eyes: 100% in the TL group and 70% in the LT group. In the LT group, a type 2 BB formed in 2 corneas and one cornea was perforated during cannula insertion. Type 1 BB was achieved after one attempt in 90% of eyes in the TL group and in 57% in the LT group.Conclusion: Shaping the tunnel before rather than after lamellar incision may be more effective for obtaining a type 1 BB by air injection.Keywords: deep anterior lamellar keratoplasty, femtosecond laser, big bubble, intrastromal incision, lamellar incision
format article
author Pedrotti E
Bonacci E
De Rossi A
Bonetto J
Chierego C
Fasolo A
De Gregorio A
Marchini G
author_facet Pedrotti E
Bonacci E
De Rossi A
Bonetto J
Chierego C
Fasolo A
De Gregorio A
Marchini G
author_sort Pedrotti E
title Femtosecond Laser-Assisted Big-Bubble Deep Anterior Lamellar Keratoplasty
title_short Femtosecond Laser-Assisted Big-Bubble Deep Anterior Lamellar Keratoplasty
title_full Femtosecond Laser-Assisted Big-Bubble Deep Anterior Lamellar Keratoplasty
title_fullStr Femtosecond Laser-Assisted Big-Bubble Deep Anterior Lamellar Keratoplasty
title_full_unstemmed Femtosecond Laser-Assisted Big-Bubble Deep Anterior Lamellar Keratoplasty
title_sort femtosecond laser-assisted big-bubble deep anterior lamellar keratoplasty
publisher Dove Medical Press
publishDate 2021
url https://doaj.org/article/588f650cf96d4eec9daaf33f5cd7804d
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