Structure of the complete, membrane-assembled COPII coat reveals a complex interaction network
Cytosolic coat proteins capture secretory cargo and sculpt membrane carriers for intracellular transport, such as COPII which mediates Endoplasmic Reticulum to Golgi trafficking of thousands of cargoes. Here authors visualise the complete, membrane-assembled COPII coat by cryo-electron tomography an...
Guardado en:
Autores principales: | , , , , , |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/5898464a97104058b571bede3a2948c3 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
id |
oai:doaj.org-article:5898464a97104058b571bede3a2948c3 |
---|---|
record_format |
dspace |
spelling |
oai:doaj.org-article:5898464a97104058b571bede3a2948c32021-12-02T18:18:03ZStructure of the complete, membrane-assembled COPII coat reveals a complex interaction network10.1038/s41467-021-22110-62041-1723https://doaj.org/article/5898464a97104058b571bede3a2948c32021-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22110-6https://doaj.org/toc/2041-1723Cytosolic coat proteins capture secretory cargo and sculpt membrane carriers for intracellular transport, such as COPII which mediates Endoplasmic Reticulum to Golgi trafficking of thousands of cargoes. Here authors visualise the complete, membrane-assembled COPII coat by cryo-electron tomography and subtomogram averaging, revealing the full network of interactions within and between coat layers.Joshua HutchingsViktoriya G. StanchevaNick R. BrownAlan C. M. CheungElizabeth A. MillerGiulia ZanettiNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-13 (2021) |
institution |
DOAJ |
collection |
DOAJ |
language |
EN |
topic |
Science Q |
spellingShingle |
Science Q Joshua Hutchings Viktoriya G. Stancheva Nick R. Brown Alan C. M. Cheung Elizabeth A. Miller Giulia Zanetti Structure of the complete, membrane-assembled COPII coat reveals a complex interaction network |
description |
Cytosolic coat proteins capture secretory cargo and sculpt membrane carriers for intracellular transport, such as COPII which mediates Endoplasmic Reticulum to Golgi trafficking of thousands of cargoes. Here authors visualise the complete, membrane-assembled COPII coat by cryo-electron tomography and subtomogram averaging, revealing the full network of interactions within and between coat layers. |
format |
article |
author |
Joshua Hutchings Viktoriya G. Stancheva Nick R. Brown Alan C. M. Cheung Elizabeth A. Miller Giulia Zanetti |
author_facet |
Joshua Hutchings Viktoriya G. Stancheva Nick R. Brown Alan C. M. Cheung Elizabeth A. Miller Giulia Zanetti |
author_sort |
Joshua Hutchings |
title |
Structure of the complete, membrane-assembled COPII coat reveals a complex interaction network |
title_short |
Structure of the complete, membrane-assembled COPII coat reveals a complex interaction network |
title_full |
Structure of the complete, membrane-assembled COPII coat reveals a complex interaction network |
title_fullStr |
Structure of the complete, membrane-assembled COPII coat reveals a complex interaction network |
title_full_unstemmed |
Structure of the complete, membrane-assembled COPII coat reveals a complex interaction network |
title_sort |
structure of the complete, membrane-assembled copii coat reveals a complex interaction network |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/5898464a97104058b571bede3a2948c3 |
work_keys_str_mv |
AT joshuahutchings structureofthecompletemembraneassembledcopiicoatrevealsacomplexinteractionnetwork AT viktoriyagstancheva structureofthecompletemembraneassembledcopiicoatrevealsacomplexinteractionnetwork AT nickrbrown structureofthecompletemembraneassembledcopiicoatrevealsacomplexinteractionnetwork AT alancmcheung structureofthecompletemembraneassembledcopiicoatrevealsacomplexinteractionnetwork AT elizabethamiller structureofthecompletemembraneassembledcopiicoatrevealsacomplexinteractionnetwork AT giuliazanetti structureofthecompletemembraneassembledcopiicoatrevealsacomplexinteractionnetwork |
_version_ |
1718378274477834240 |