Structure of the complete, membrane-assembled COPII coat reveals a complex interaction network

Cytosolic coat proteins capture secretory cargo and sculpt membrane carriers for intracellular transport, such as COPII which mediates Endoplasmic Reticulum to Golgi trafficking of thousands of cargoes. Here authors visualise the complete, membrane-assembled COPII coat by cryo-electron tomography an...

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Autores principales: Joshua Hutchings, Viktoriya G. Stancheva, Nick R. Brown, Alan C. M. Cheung, Elizabeth A. Miller, Giulia Zanetti
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/5898464a97104058b571bede3a2948c3
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spelling oai:doaj.org-article:5898464a97104058b571bede3a2948c32021-12-02T18:18:03ZStructure of the complete, membrane-assembled COPII coat reveals a complex interaction network10.1038/s41467-021-22110-62041-1723https://doaj.org/article/5898464a97104058b571bede3a2948c32021-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22110-6https://doaj.org/toc/2041-1723Cytosolic coat proteins capture secretory cargo and sculpt membrane carriers for intracellular transport, such as COPII which mediates Endoplasmic Reticulum to Golgi trafficking of thousands of cargoes. Here authors visualise the complete, membrane-assembled COPII coat by cryo-electron tomography and subtomogram averaging, revealing the full network of interactions within and between coat layers.Joshua HutchingsViktoriya G. StanchevaNick R. BrownAlan C. M. CheungElizabeth A. MillerGiulia ZanettiNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Joshua Hutchings
Viktoriya G. Stancheva
Nick R. Brown
Alan C. M. Cheung
Elizabeth A. Miller
Giulia Zanetti
Structure of the complete, membrane-assembled COPII coat reveals a complex interaction network
description Cytosolic coat proteins capture secretory cargo and sculpt membrane carriers for intracellular transport, such as COPII which mediates Endoplasmic Reticulum to Golgi trafficking of thousands of cargoes. Here authors visualise the complete, membrane-assembled COPII coat by cryo-electron tomography and subtomogram averaging, revealing the full network of interactions within and between coat layers.
format article
author Joshua Hutchings
Viktoriya G. Stancheva
Nick R. Brown
Alan C. M. Cheung
Elizabeth A. Miller
Giulia Zanetti
author_facet Joshua Hutchings
Viktoriya G. Stancheva
Nick R. Brown
Alan C. M. Cheung
Elizabeth A. Miller
Giulia Zanetti
author_sort Joshua Hutchings
title Structure of the complete, membrane-assembled COPII coat reveals a complex interaction network
title_short Structure of the complete, membrane-assembled COPII coat reveals a complex interaction network
title_full Structure of the complete, membrane-assembled COPII coat reveals a complex interaction network
title_fullStr Structure of the complete, membrane-assembled COPII coat reveals a complex interaction network
title_full_unstemmed Structure of the complete, membrane-assembled COPII coat reveals a complex interaction network
title_sort structure of the complete, membrane-assembled copii coat reveals a complex interaction network
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/5898464a97104058b571bede3a2948c3
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