Water orientation and dynamics in the closed and open influenza B virus M2 proton channels

To understand how water in the channel made of the influenza B M2 protein mediates proton transport across the lipid membrane, Gelenter et al. investigate the water orientation and dynamics. This study suggests that faster dynamics and higher orientational order of water molecules in the open channe...

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Autores principales:	Martin D. Gelenter, Venkata S. Mandala, Michiel J. M. Niesen, Dina A. Sharon, Aurelio J. Dregni, Adam P. Willard, Mei Hong
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/589f0e86237b4a8cafe159e50811cbe3
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spelling	oai:doaj.org-article:589f0e86237b4a8cafe159e50811cbe32021-12-02T13:15:51ZWater orientation and dynamics in the closed and open influenza B virus M2 proton channels10.1038/s42003-021-01847-22399-3642https://doaj.org/article/589f0e86237b4a8cafe159e50811cbe32021-03-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-01847-2https://doaj.org/toc/2399-3642To understand how water in the channel made of the influenza B M2 protein mediates proton transport across the lipid membrane, Gelenter et al. investigate the water orientation and dynamics. This study suggests that faster dynamics and higher orientational order of water molecules in the open channel compared to the closed one establish the water network structure that is necessary for proton hopping.Martin D. GelenterVenkata S. MandalaMichiel J. M. NiesenDina A. SharonAurelio J. DregniAdam P. WillardMei HongNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Martin D. Gelenter Venkata S. Mandala Michiel J. M. Niesen Dina A. Sharon Aurelio J. Dregni Adam P. Willard Mei Hong Water orientation and dynamics in the closed and open influenza B virus M2 proton channels
description	To understand how water in the channel made of the influenza B M2 protein mediates proton transport across the lipid membrane, Gelenter et al. investigate the water orientation and dynamics. This study suggests that faster dynamics and higher orientational order of water molecules in the open channel compared to the closed one establish the water network structure that is necessary for proton hopping.
format	article
author	Martin D. Gelenter Venkata S. Mandala Michiel J. M. Niesen Dina A. Sharon Aurelio J. Dregni Adam P. Willard Mei Hong
author_facet	Martin D. Gelenter Venkata S. Mandala Michiel J. M. Niesen Dina A. Sharon Aurelio J. Dregni Adam P. Willard Mei Hong
author_sort	Martin D. Gelenter
title	Water orientation and dynamics in the closed and open influenza B virus M2 proton channels
title_short	Water orientation and dynamics in the closed and open influenza B virus M2 proton channels
title_full	Water orientation and dynamics in the closed and open influenza B virus M2 proton channels
title_fullStr	Water orientation and dynamics in the closed and open influenza B virus M2 proton channels
title_full_unstemmed	Water orientation and dynamics in the closed and open influenza B virus M2 proton channels
title_sort	water orientation and dynamics in the closed and open influenza b virus m2 proton channels
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/589f0e86237b4a8cafe159e50811cbe3
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Water orientation and dynamics in the closed and open influenza B virus M2 proton channels

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