Acetyl-CoA derived from hepatic mitochondrial fatty acid β-oxidation aggravates inflammation by enhancing p65 acetylation

Summary: Acetylation coordinates many biological processes to ensure cells respond appropriately to nutrients. However, how acetylation regulates lipid surplus-induced inflammation remains poorly understood. Here, we found that a high-fat diet (HFD) enhanced mitochondrial fatty acid β-oxidation, whi...

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Bibliographic Details
Main Authors: Qiang Chen, Jianlong Du, Kun Cui, Wei Fang, Zengqi Zhao, Qiuchi Chen, Kangsen Mai, Qinghui Ai
Format: article
Language:EN
Published: Elsevier 2021
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Online Access:https://doaj.org/article/58a50713eb7c4de4b0905def7ddb8dbc
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