The protein kinase CK2 catalytic domain from Plasmodium falciparum: crystal structure, tyrosine kinase activity and inhibition

Abstract Malaria causes every year over half-a-million deaths. The emergence of parasites resistant to available treatments makes the identification of new targets and their inhibitors an urgent task for the development of novel anti-malaria drugs. Protein kinase CK2 is an evolutionary-conserved euk...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: David Ruiz-Carrillo, Jianqing Lin, Abbas El Sahili, Meng Wei, Siu Kwan Sze, Peter C. F. Cheung, Christian Doerig, Julien Lescar
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
Materias:
R
Q
Acceso en línea:https://doaj.org/article/58ab85b505ca437a9526f9ae8fbfbcc3
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!