Stat3 regulates centrosome clustering in cancer cells via Stathmin/PLK1

Cancer cells have amplified centrosomes and deal with this abnormality by clustering them together so that they can be segregated in daughter cells. Here the authors perform a screening looking for inhibitors of this clustering process and find that STAT3 regulates this process independently of its...

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Bibliographic Details
Main Authors: Edward J. Morris, Eiko Kawamura, Jordan A. Gillespie, Aruna Balgi, Nagarajan Kannan, William J. Muller, Michel Roberge, Shoukat Dedhar
Format: article
Language:EN
Published: Nature Portfolio 2017
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Online Access:https://doaj.org/article/58af0d7ff4e94bbd92f3feae3e7e8595
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