Evaluation of the Prevalence and Risk of Metabolic Syndrome in Vitiligo Patients

Background: Vitiligo is a common disease of the skin, affecting epidermis and hair follicles. Both genders are affected. The main pathogenic mechanism of the disease is the destruction or inhibition of the epidermal melanocytes which is manifested clinically by presence of variable sized areas of sk...

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Autores principales:	Eman Rashed, Ibrahim Fouda, Emad Elgmal
Formato:	article
Lenguaje:	EN
Publicado:	Al-Azhar University, Faculty of Medicine (Damietta) 2019
Materias:	vitiligo segmental vitiligo interleukin Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/58b2a1e363234de9ae119057f8251856
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spelling	oai:doaj.org-article:58b2a1e363234de9ae119057f82518562021-12-02T10:38:27ZEvaluation of the Prevalence and Risk of Metabolic Syndrome in Vitiligo Patients2636-41742682-378010.21608/ijma.2019.13576.1011https://doaj.org/article/58b2a1e363234de9ae119057f82518562019-10-01T00:00:00Zhttps://ijma.journals.ekb.eg/article_45442_40d0e68ac7697a24bd4595b7f15c7c76.pdfhttps://doaj.org/toc/2636-4174https://doaj.org/toc/2682-3780Background: Vitiligo is a common disease of the skin, affecting epidermis and hair follicles. Both genders are affected. The main pathogenic mechanism of the disease is the destruction or inhibition of the epidermal melanocytes which is manifested clinically by presence of variable sized areas of skin depigmentation that can affect any site of the body.Aim of the work: To estimate the prevalence and risk of metabolic syndrome in vitiligo patients.Patients and Methods: This is a case control study that was conducted on 90 patients with vitiligo recruited from outpatient clinic, dermatology department of Al Azhar University Hospital in Damietta, and 60 healthy controls. Full history was taken from all the subjects included in the study. The cases were also subjected to careful general examination and dermatological examination to determine the site and the type of the lesion and the presence of any dermatological diseases, laboratory investigations including HDL, TG and FBS were done.Results: In this study we found that 35.6% of cases have metabolic syndrome while 33.3% of healthy controls have metabolic syndrome. We also found that there is no relation between presence of metabolic syndrome and disease extent, progression or stage.Conclusion: Incidence of metabolic syndrome is slightly higher in cases with vitiligo as compared to the control group. Presence of metabolic syndrome is not associated with disease severity, extent or stage.Eman RashedIbrahim FoudaEmad ElgmalAl-Azhar University, Faculty of Medicine (Damietta)articlevitiligosegmental vitiligointerleukinMedicine (General)R5-920ENInternational Journal of Medical Arts, Vol 1, Iss 2, Pp 91-97 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	vitiligo segmental vitiligo interleukin Medicine (General) R5-920
spellingShingle	vitiligo segmental vitiligo interleukin Medicine (General) R5-920 Eman Rashed Ibrahim Fouda Emad Elgmal Evaluation of the Prevalence and Risk of Metabolic Syndrome in Vitiligo Patients
description	Background: Vitiligo is a common disease of the skin, affecting epidermis and hair follicles. Both genders are affected. The main pathogenic mechanism of the disease is the destruction or inhibition of the epidermal melanocytes which is manifested clinically by presence of variable sized areas of skin depigmentation that can affect any site of the body.Aim of the work: To estimate the prevalence and risk of metabolic syndrome in vitiligo patients.Patients and Methods: This is a case control study that was conducted on 90 patients with vitiligo recruited from outpatient clinic, dermatology department of Al Azhar University Hospital in Damietta, and 60 healthy controls. Full history was taken from all the subjects included in the study. The cases were also subjected to careful general examination and dermatological examination to determine the site and the type of the lesion and the presence of any dermatological diseases, laboratory investigations including HDL, TG and FBS were done.Results: In this study we found that 35.6% of cases have metabolic syndrome while 33.3% of healthy controls have metabolic syndrome. We also found that there is no relation between presence of metabolic syndrome and disease extent, progression or stage.Conclusion: Incidence of metabolic syndrome is slightly higher in cases with vitiligo as compared to the control group. Presence of metabolic syndrome is not associated with disease severity, extent or stage.
format	article
author	Eman Rashed Ibrahim Fouda Emad Elgmal
author_facet	Eman Rashed Ibrahim Fouda Emad Elgmal
author_sort	Eman Rashed
title	Evaluation of the Prevalence and Risk of Metabolic Syndrome in Vitiligo Patients
title_short	Evaluation of the Prevalence and Risk of Metabolic Syndrome in Vitiligo Patients
title_full	Evaluation of the Prevalence and Risk of Metabolic Syndrome in Vitiligo Patients
title_fullStr	Evaluation of the Prevalence and Risk of Metabolic Syndrome in Vitiligo Patients
title_full_unstemmed	Evaluation of the Prevalence and Risk of Metabolic Syndrome in Vitiligo Patients
title_sort	evaluation of the prevalence and risk of metabolic syndrome in vitiligo patients
publisher	Al-Azhar University, Faculty of Medicine (Damietta)
publishDate	2019
url	https://doaj.org/article/58b2a1e363234de9ae119057f8251856
work_keys_str_mv	AT emanrashed evaluationoftheprevalenceandriskofmetabolicsyndromeinvitiligopatients AT ibrahimfouda evaluationoftheprevalenceandriskofmetabolicsyndromeinvitiligopatients AT emadelgmal evaluationoftheprevalenceandriskofmetabolicsyndromeinvitiligopatients
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Evaluation of the Prevalence and Risk of Metabolic Syndrome in Vitiligo Patients

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