Cross-lineage protection by human antibodies binding the influenza B hemagglutinin
Immune recognition of Influenza B virus (IBV) is poorly understood. Here, Liu et al. use flow cytometry to characterize IBV-specific memory B cell responses following seasonal vaccination and show that elicited cross-reactive antibodies can protect against infection, providing a platform for vaccine...
Guardado en:
Autores principales: | , , , , , , , , , , |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2019
|
Materias: | |
Acceso en línea: | https://doaj.org/article/58b80794ab9343afae27758863410014 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
id |
oai:doaj.org-article:58b80794ab9343afae27758863410014 |
---|---|
record_format |
dspace |
spelling |
oai:doaj.org-article:58b80794ab9343afae277588634100142021-12-02T17:32:55ZCross-lineage protection by human antibodies binding the influenza B hemagglutinin10.1038/s41467-018-08165-y2041-1723https://doaj.org/article/58b80794ab9343afae277588634100142019-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-08165-yhttps://doaj.org/toc/2041-1723Immune recognition of Influenza B virus (IBV) is poorly understood. Here, Liu et al. use flow cytometry to characterize IBV-specific memory B cell responses following seasonal vaccination and show that elicited cross-reactive antibodies can protect against infection, providing a platform for vaccine design.Yi LiuHyon-Xhi TanMarios KoutsakosSinthujan JegaskandaRobyn EsterbauerDanielle TilmanisMalet AbanKatherine KedzierskaAeron C. HurtStephen J. KentAdam K. WheatleyNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-13 (2019) |
institution |
DOAJ |
collection |
DOAJ |
language |
EN |
topic |
Science Q |
spellingShingle |
Science Q Yi Liu Hyon-Xhi Tan Marios Koutsakos Sinthujan Jegaskanda Robyn Esterbauer Danielle Tilmanis Malet Aban Katherine Kedzierska Aeron C. Hurt Stephen J. Kent Adam K. Wheatley Cross-lineage protection by human antibodies binding the influenza B hemagglutinin |
description |
Immune recognition of Influenza B virus (IBV) is poorly understood. Here, Liu et al. use flow cytometry to characterize IBV-specific memory B cell responses following seasonal vaccination and show that elicited cross-reactive antibodies can protect against infection, providing a platform for vaccine design. |
format |
article |
author |
Yi Liu Hyon-Xhi Tan Marios Koutsakos Sinthujan Jegaskanda Robyn Esterbauer Danielle Tilmanis Malet Aban Katherine Kedzierska Aeron C. Hurt Stephen J. Kent Adam K. Wheatley |
author_facet |
Yi Liu Hyon-Xhi Tan Marios Koutsakos Sinthujan Jegaskanda Robyn Esterbauer Danielle Tilmanis Malet Aban Katherine Kedzierska Aeron C. Hurt Stephen J. Kent Adam K. Wheatley |
author_sort |
Yi Liu |
title |
Cross-lineage protection by human antibodies binding the influenza B hemagglutinin |
title_short |
Cross-lineage protection by human antibodies binding the influenza B hemagglutinin |
title_full |
Cross-lineage protection by human antibodies binding the influenza B hemagglutinin |
title_fullStr |
Cross-lineage protection by human antibodies binding the influenza B hemagglutinin |
title_full_unstemmed |
Cross-lineage protection by human antibodies binding the influenza B hemagglutinin |
title_sort |
cross-lineage protection by human antibodies binding the influenza b hemagglutinin |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/58b80794ab9343afae27758863410014 |
work_keys_str_mv |
AT yiliu crosslineageprotectionbyhumanantibodiesbindingtheinfluenzabhemagglutinin AT hyonxhitan crosslineageprotectionbyhumanantibodiesbindingtheinfluenzabhemagglutinin AT marioskoutsakos crosslineageprotectionbyhumanantibodiesbindingtheinfluenzabhemagglutinin AT sinthujanjegaskanda crosslineageprotectionbyhumanantibodiesbindingtheinfluenzabhemagglutinin AT robynesterbauer crosslineageprotectionbyhumanantibodiesbindingtheinfluenzabhemagglutinin AT danielletilmanis crosslineageprotectionbyhumanantibodiesbindingtheinfluenzabhemagglutinin AT maletaban crosslineageprotectionbyhumanantibodiesbindingtheinfluenzabhemagglutinin AT katherinekedzierska crosslineageprotectionbyhumanantibodiesbindingtheinfluenzabhemagglutinin AT aeronchurt crosslineageprotectionbyhumanantibodiesbindingtheinfluenzabhemagglutinin AT stephenjkent crosslineageprotectionbyhumanantibodiesbindingtheinfluenzabhemagglutinin AT adamkwheatley crosslineageprotectionbyhumanantibodiesbindingtheinfluenzabhemagglutinin |
_version_ |
1718380120880709632 |