Cross-lineage protection by human antibodies binding the influenza B hemagglutinin

Immune recognition of Influenza B virus (IBV) is poorly understood. Here, Liu et al. use flow cytometry to characterize IBV-specific memory B cell responses following seasonal vaccination and show that elicited cross-reactive antibodies can protect against infection, providing a platform for vaccine...

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Autores principales: Yi Liu, Hyon-Xhi Tan, Marios Koutsakos, Sinthujan Jegaskanda, Robyn Esterbauer, Danielle Tilmanis, Malet Aban, Katherine Kedzierska, Aeron C. Hurt, Stephen J. Kent, Adam K. Wheatley
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Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/58b80794ab9343afae27758863410014
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spelling oai:doaj.org-article:58b80794ab9343afae277588634100142021-12-02T17:32:55ZCross-lineage protection by human antibodies binding the influenza B hemagglutinin10.1038/s41467-018-08165-y2041-1723https://doaj.org/article/58b80794ab9343afae277588634100142019-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-08165-yhttps://doaj.org/toc/2041-1723Immune recognition of Influenza B virus (IBV) is poorly understood. Here, Liu et al. use flow cytometry to characterize IBV-specific memory B cell responses following seasonal vaccination and show that elicited cross-reactive antibodies can protect against infection, providing a platform for vaccine design.Yi LiuHyon-Xhi TanMarios KoutsakosSinthujan JegaskandaRobyn EsterbauerDanielle TilmanisMalet AbanKatherine KedzierskaAeron C. HurtStephen J. KentAdam K. WheatleyNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Yi Liu
Hyon-Xhi Tan
Marios Koutsakos
Sinthujan Jegaskanda
Robyn Esterbauer
Danielle Tilmanis
Malet Aban
Katherine Kedzierska
Aeron C. Hurt
Stephen J. Kent
Adam K. Wheatley
Cross-lineage protection by human antibodies binding the influenza B hemagglutinin
description Immune recognition of Influenza B virus (IBV) is poorly understood. Here, Liu et al. use flow cytometry to characterize IBV-specific memory B cell responses following seasonal vaccination and show that elicited cross-reactive antibodies can protect against infection, providing a platform for vaccine design.
format article
author Yi Liu
Hyon-Xhi Tan
Marios Koutsakos
Sinthujan Jegaskanda
Robyn Esterbauer
Danielle Tilmanis
Malet Aban
Katherine Kedzierska
Aeron C. Hurt
Stephen J. Kent
Adam K. Wheatley
author_facet Yi Liu
Hyon-Xhi Tan
Marios Koutsakos
Sinthujan Jegaskanda
Robyn Esterbauer
Danielle Tilmanis
Malet Aban
Katherine Kedzierska
Aeron C. Hurt
Stephen J. Kent
Adam K. Wheatley
author_sort Yi Liu
title Cross-lineage protection by human antibodies binding the influenza B hemagglutinin
title_short Cross-lineage protection by human antibodies binding the influenza B hemagglutinin
title_full Cross-lineage protection by human antibodies binding the influenza B hemagglutinin
title_fullStr Cross-lineage protection by human antibodies binding the influenza B hemagglutinin
title_full_unstemmed Cross-lineage protection by human antibodies binding the influenza B hemagglutinin
title_sort cross-lineage protection by human antibodies binding the influenza b hemagglutinin
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/58b80794ab9343afae27758863410014
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