The identification of trans-acting factors that regulate the expression of GDF5 via the osteoarthritis susceptibility SNP rs143383.
rs143383 is a C to T transition SNP located in the 5'untranslated region (5'UTR) of the growth differentiation factor 5 gene GDF5. The T allele of the SNP is associated with increased risk of osteoarthritis (OA) in Europeans and in Asians. This susceptibility is mediated by the T allele pr...
Saved in:
Main Authors: | Catherine M Syddall, Louise N Reynard, David A Young, John Loughlin |
---|---|
Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2013
|
Subjects: | |
Online Access: | https://doaj.org/article/58b8e7f13aab4c6a809551ebf33ed8a2 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Association between the PLTP rs4810479 SNP and Serum Lipid Traits in the Chinese Maonan and Han Populations
by: Fen-Han Zhang, et al.
Published: (2021) -
trans-Acting Factors and cis Elements Involved in the Human Inactive X Chromosome Organization and Compaction
by: Zhuo Sun, et al.
Published: (2021) -
Functional Analysis of DNMT1 SNPs (rs2228611 and rs2114724) Associated with Schizophrenia
by: Sonal Saxena, et al.
Published: (2021) -
Estimation of non-null SNP effect size distributions enables the detection of enriched genes underlying complex traits.
by: Wei Cheng, et al.
Published: (2020) -
Associations between ADIPOQ rs2241766 SNP and breast cancer risk: a systematic review and a meta-analysis
by: Xue Hu, et al.
Published: (2021)