Advances in Cardiac Pacing: Arrhythmia Prediction, Prevention and Control Strategies
Cardiac arrhythmias constitute a tremendous burden on healthcare and are the leading cause of mortality worldwide. An alarming number of people have been reported to manifest sudden cardiac death as the first symptom of cardiac arrhythmias, accounting for about 20% of all deaths annually. Furthermor...
Guardado en:
| Autores principales: | , , , , , , , , , , |
|---|---|
| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Frontiers Media S.A.
2021
|
| Materias: | |
| Acceso en línea: | https://doaj.org/article/58d1886ef85842deb294f1ff463896b8 |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| id |
oai:doaj.org-article:58d1886ef85842deb294f1ff463896b8 |
|---|---|
| record_format |
dspace |
| spelling |
oai:doaj.org-article:58d1886ef85842deb294f1ff463896b82021-12-02T09:58:21ZAdvances in Cardiac Pacing: Arrhythmia Prediction, Prevention and Control Strategies1664-042X10.3389/fphys.2021.783241https://doaj.org/article/58d1886ef85842deb294f1ff463896b82021-12-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fphys.2021.783241/fullhttps://doaj.org/toc/1664-042XCardiac arrhythmias constitute a tremendous burden on healthcare and are the leading cause of mortality worldwide. An alarming number of people have been reported to manifest sudden cardiac death as the first symptom of cardiac arrhythmias, accounting for about 20% of all deaths annually. Furthermore, patients prone to atrial tachyarrhythmias such as atrial flutter and fibrillation often have associated comorbidities including hypertension, ischemic heart disease, valvular cardiomyopathy and increased risk of stroke. Technological advances in electrical stimulation and sensing modalities have led to the proliferation of medical devices including pacemakers and implantable defibrillators, aiming to restore normal cardiac rhythm. However, given the complex spatiotemporal dynamics and non-linearity of the human heart, predicting the onset of arrhythmias and preventing the transition from steady state to unstable rhythms has been an extremely challenging task. Defibrillatory shocks still remain the primary clinical intervention for lethal ventricular arrhythmias, yet patients with implantable cardioverter defibrillators often suffer from inappropriate shocks due to false positives and reduced quality of life. Here, we aim to present a comprehensive review of the current advances in cardiac arrhythmia prediction, prevention and control strategies. We provide an overview of traditional clinical arrhythmia management methods and describe promising potential pacing techniques for predicting the onset of abnormal rhythms and effectively suppressing cardiac arrhythmias. We also offer a clinical perspective on bridging the gap between basic and clinical science that would aid in the assimilation of promising anti-arrhythmic pacing strategies.Mehrie Harshad PatelShrikanth SampathAnoushka KapoorDevanshi Narendra DamaniNikitha ChellapuramApurva Bhavana ChallaManmeet Pal KaurRichard D. WaltonRichard D. WaltonRichard D. WaltonStavros StavrakisShivaram P. ArunachalamShivaram P. ArunachalamShivaram P. ArunachalamShivaram P. ArunachalamKanchan KulkarniKanchan KulkarniKanchan KulkarniFrontiers Media S.A.articlearrhythmiaspacingalternanscontrolnon-linear dynamicspredictionPhysiologyQP1-981ENFrontiers in Physiology, Vol 12 (2021) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
arrhythmias pacing alternans control non-linear dynamics prediction Physiology QP1-981 |
| spellingShingle |
arrhythmias pacing alternans control non-linear dynamics prediction Physiology QP1-981 Mehrie Harshad Patel Shrikanth Sampath Anoushka Kapoor Devanshi Narendra Damani Nikitha Chellapuram Apurva Bhavana Challa Manmeet Pal Kaur Richard D. Walton Richard D. Walton Richard D. Walton Stavros Stavrakis Shivaram P. Arunachalam Shivaram P. Arunachalam Shivaram P. Arunachalam Shivaram P. Arunachalam Kanchan Kulkarni Kanchan Kulkarni Kanchan Kulkarni Advances in Cardiac Pacing: Arrhythmia Prediction, Prevention and Control Strategies |
| description |
Cardiac arrhythmias constitute a tremendous burden on healthcare and are the leading cause of mortality worldwide. An alarming number of people have been reported to manifest sudden cardiac death as the first symptom of cardiac arrhythmias, accounting for about 20% of all deaths annually. Furthermore, patients prone to atrial tachyarrhythmias such as atrial flutter and fibrillation often have associated comorbidities including hypertension, ischemic heart disease, valvular cardiomyopathy and increased risk of stroke. Technological advances in electrical stimulation and sensing modalities have led to the proliferation of medical devices including pacemakers and implantable defibrillators, aiming to restore normal cardiac rhythm. However, given the complex spatiotemporal dynamics and non-linearity of the human heart, predicting the onset of arrhythmias and preventing the transition from steady state to unstable rhythms has been an extremely challenging task. Defibrillatory shocks still remain the primary clinical intervention for lethal ventricular arrhythmias, yet patients with implantable cardioverter defibrillators often suffer from inappropriate shocks due to false positives and reduced quality of life. Here, we aim to present a comprehensive review of the current advances in cardiac arrhythmia prediction, prevention and control strategies. We provide an overview of traditional clinical arrhythmia management methods and describe promising potential pacing techniques for predicting the onset of abnormal rhythms and effectively suppressing cardiac arrhythmias. We also offer a clinical perspective on bridging the gap between basic and clinical science that would aid in the assimilation of promising anti-arrhythmic pacing strategies. |
| format |
article |
| author |
Mehrie Harshad Patel Shrikanth Sampath Anoushka Kapoor Devanshi Narendra Damani Nikitha Chellapuram Apurva Bhavana Challa Manmeet Pal Kaur Richard D. Walton Richard D. Walton Richard D. Walton Stavros Stavrakis Shivaram P. Arunachalam Shivaram P. Arunachalam Shivaram P. Arunachalam Shivaram P. Arunachalam Kanchan Kulkarni Kanchan Kulkarni Kanchan Kulkarni |
| author_facet |
Mehrie Harshad Patel Shrikanth Sampath Anoushka Kapoor Devanshi Narendra Damani Nikitha Chellapuram Apurva Bhavana Challa Manmeet Pal Kaur Richard D. Walton Richard D. Walton Richard D. Walton Stavros Stavrakis Shivaram P. Arunachalam Shivaram P. Arunachalam Shivaram P. Arunachalam Shivaram P. Arunachalam Kanchan Kulkarni Kanchan Kulkarni Kanchan Kulkarni |
| author_sort |
Mehrie Harshad Patel |
| title |
Advances in Cardiac Pacing: Arrhythmia Prediction, Prevention and Control Strategies |
| title_short |
Advances in Cardiac Pacing: Arrhythmia Prediction, Prevention and Control Strategies |
| title_full |
Advances in Cardiac Pacing: Arrhythmia Prediction, Prevention and Control Strategies |
| title_fullStr |
Advances in Cardiac Pacing: Arrhythmia Prediction, Prevention and Control Strategies |
| title_full_unstemmed |
Advances in Cardiac Pacing: Arrhythmia Prediction, Prevention and Control Strategies |
| title_sort |
advances in cardiac pacing: arrhythmia prediction, prevention and control strategies |
| publisher |
Frontiers Media S.A. |
| publishDate |
2021 |
| url |
https://doaj.org/article/58d1886ef85842deb294f1ff463896b8 |
| work_keys_str_mv |
AT mehrieharshadpatel advancesincardiacpacingarrhythmiapredictionpreventionandcontrolstrategies AT shrikanthsampath advancesincardiacpacingarrhythmiapredictionpreventionandcontrolstrategies AT anoushkakapoor advancesincardiacpacingarrhythmiapredictionpreventionandcontrolstrategies AT devanshinarendradamani advancesincardiacpacingarrhythmiapredictionpreventionandcontrolstrategies AT nikithachellapuram advancesincardiacpacingarrhythmiapredictionpreventionandcontrolstrategies AT apurvabhavanachalla advancesincardiacpacingarrhythmiapredictionpreventionandcontrolstrategies AT manmeetpalkaur advancesincardiacpacingarrhythmiapredictionpreventionandcontrolstrategies AT richarddwalton advancesincardiacpacingarrhythmiapredictionpreventionandcontrolstrategies AT richarddwalton advancesincardiacpacingarrhythmiapredictionpreventionandcontrolstrategies AT richarddwalton advancesincardiacpacingarrhythmiapredictionpreventionandcontrolstrategies AT stavrosstavrakis advancesincardiacpacingarrhythmiapredictionpreventionandcontrolstrategies AT shivaramparunachalam advancesincardiacpacingarrhythmiapredictionpreventionandcontrolstrategies AT shivaramparunachalam advancesincardiacpacingarrhythmiapredictionpreventionandcontrolstrategies AT shivaramparunachalam advancesincardiacpacingarrhythmiapredictionpreventionandcontrolstrategies AT shivaramparunachalam advancesincardiacpacingarrhythmiapredictionpreventionandcontrolstrategies AT kanchankulkarni advancesincardiacpacingarrhythmiapredictionpreventionandcontrolstrategies AT kanchankulkarni advancesincardiacpacingarrhythmiapredictionpreventionandcontrolstrategies AT kanchankulkarni advancesincardiacpacingarrhythmiapredictionpreventionandcontrolstrategies |
| _version_ |
1718397881787875328 |