Insight Into Nicotinamide Adenine Dinucleotide Homeostasis as a Targetable Metabolic Pathway in Colorectal Cancer

Tumour cells modify their cellular metabolism with the aim to sustain uncontrolled proliferation. Cancer cells necessitate adequate amounts of NAD and NADPH to support several enzymes that are usually overexpressed and/or overactivated. Nicotinamide adenine dinucleotide (NAD) is an essential cofacto...

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Bibliographic Details
Main Authors: Giorgia Colombo, Edoardo Luigi Maria Gelardi, Federica Carolina Balestrero, Marianna Moro, Cristina Travelli, Armando A. Genazzani
Format: article
Language:EN
Published: Frontiers Media S.A. 2021
Subjects:
NAD
Online Access:https://doaj.org/article/58d731c9ede84435a1cb782dd86f6700
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