Risk Factors for Early Recurrence of Gallstones in Patients Undergoing Laparoscopy Combined With Choledochoscopic Lithotomy: A Single-Center Prospective Study

Objective: For patients with gallstones, laparoscopy combined with choledochoscopic lithotomy is a therapeutic surgical option for preservation rather than the removal of the gallbladder. However, postoperative recurrence of gallstones is a key concern for both patients and surgeons. This prospectiv...

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Autores principales: Bo Wang, Anhua Huang, Min Jiang, Haidong Li, Wenqing Bao, Kan Ding, Zhaoyan Jiang, Gang Zhao, Hai Hu
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Publicado: Frontiers Media S.A. 2021
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spelling oai:doaj.org-article:58f1e46b4831420486a0058ad47bf9d92021-11-30T17:12:27ZRisk Factors for Early Recurrence of Gallstones in Patients Undergoing Laparoscopy Combined With Choledochoscopic Lithotomy: A Single-Center Prospective Study2296-875X10.3389/fsurg.2021.759390https://doaj.org/article/58f1e46b4831420486a0058ad47bf9d92021-11-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fsurg.2021.759390/fullhttps://doaj.org/toc/2296-875XObjective: For patients with gallstones, laparoscopy combined with choledochoscopic lithotomy is a therapeutic surgical option for preservation rather than the removal of the gallbladder. However, postoperative recurrence of gallstones is a key concern for both patients and surgeons. This prospective study was performed to investigate the risk factors for early postoperative recurrence of gallstones.Methods: The clinical data of 466 patients were collected. Each patient was followed up for up to 2 years. The first follow-up visit occurred 4 months after the operation, and a follow-up visit was carried out every 6 months thereafter. The main goal of each visit was to confirm the presence or absence of gallbladder stones. The factors associated with gallstone recurrence were analyzed by univariate analysis and Cox regression.Results: In total, 466 eligible patients were included in the study, and 438 patients (180 men and 258 women) completed the 2-year postoperative follow-up. The follow-up rate was 94.0%. Recurrence of gallstones was detected in 5.71% (25/438) of the patients. Univariate analysis revealed five risk factors for the recurrence of gallstones. Multivariate Cox regression analysis showed that multiple gallstones, a gallbladder wall thickness of ≥4 mm, and a family history of gallbladder stones were the three predictive factors for postoperative recurrence of gallstones (P < 0.05).Conclusion: The overall 2-year recurrence rate of gallstones after the operation was 5.71%. Multiple gallstones, a gallbladder wall thickness of ≥4 mm, and a family history of gallstones were the three risk factors associated with early postoperative recurrence of gallstones.Bo WangAnhua HuangMin JiangHaidong LiWenqing BaoKan DingZhaoyan JiangGang ZhaoHai HuFrontiers Media S.A.articlegallstonelaparoscopy combined with choledochoscope lithotomyrisk factorsrecurrencefollow-upSurgeryRD1-811ENFrontiers in Surgery, Vol 8 (2021)
institution DOAJ
collection DOAJ
language EN
topic gallstone
laparoscopy combined with choledochoscope lithotomy
risk factors
recurrence
follow-up
Surgery
RD1-811
spellingShingle gallstone
laparoscopy combined with choledochoscope lithotomy
risk factors
recurrence
follow-up
Surgery
RD1-811
Bo Wang
Anhua Huang
Min Jiang
Haidong Li
Wenqing Bao
Kan Ding
Zhaoyan Jiang
Gang Zhao
Hai Hu
Risk Factors for Early Recurrence of Gallstones in Patients Undergoing Laparoscopy Combined With Choledochoscopic Lithotomy: A Single-Center Prospective Study
description Objective: For patients with gallstones, laparoscopy combined with choledochoscopic lithotomy is a therapeutic surgical option for preservation rather than the removal of the gallbladder. However, postoperative recurrence of gallstones is a key concern for both patients and surgeons. This prospective study was performed to investigate the risk factors for early postoperative recurrence of gallstones.Methods: The clinical data of 466 patients were collected. Each patient was followed up for up to 2 years. The first follow-up visit occurred 4 months after the operation, and a follow-up visit was carried out every 6 months thereafter. The main goal of each visit was to confirm the presence or absence of gallbladder stones. The factors associated with gallstone recurrence were analyzed by univariate analysis and Cox regression.Results: In total, 466 eligible patients were included in the study, and 438 patients (180 men and 258 women) completed the 2-year postoperative follow-up. The follow-up rate was 94.0%. Recurrence of gallstones was detected in 5.71% (25/438) of the patients. Univariate analysis revealed five risk factors for the recurrence of gallstones. Multivariate Cox regression analysis showed that multiple gallstones, a gallbladder wall thickness of ≥4 mm, and a family history of gallbladder stones were the three predictive factors for postoperative recurrence of gallstones (P < 0.05).Conclusion: The overall 2-year recurrence rate of gallstones after the operation was 5.71%. Multiple gallstones, a gallbladder wall thickness of ≥4 mm, and a family history of gallstones were the three risk factors associated with early postoperative recurrence of gallstones.
format article
author Bo Wang
Anhua Huang
Min Jiang
Haidong Li
Wenqing Bao
Kan Ding
Zhaoyan Jiang
Gang Zhao
Hai Hu
author_facet Bo Wang
Anhua Huang
Min Jiang
Haidong Li
Wenqing Bao
Kan Ding
Zhaoyan Jiang
Gang Zhao
Hai Hu
author_sort Bo Wang
title Risk Factors for Early Recurrence of Gallstones in Patients Undergoing Laparoscopy Combined With Choledochoscopic Lithotomy: A Single-Center Prospective Study
title_short Risk Factors for Early Recurrence of Gallstones in Patients Undergoing Laparoscopy Combined With Choledochoscopic Lithotomy: A Single-Center Prospective Study
title_full Risk Factors for Early Recurrence of Gallstones in Patients Undergoing Laparoscopy Combined With Choledochoscopic Lithotomy: A Single-Center Prospective Study
title_fullStr Risk Factors for Early Recurrence of Gallstones in Patients Undergoing Laparoscopy Combined With Choledochoscopic Lithotomy: A Single-Center Prospective Study
title_full_unstemmed Risk Factors for Early Recurrence of Gallstones in Patients Undergoing Laparoscopy Combined With Choledochoscopic Lithotomy: A Single-Center Prospective Study
title_sort risk factors for early recurrence of gallstones in patients undergoing laparoscopy combined with choledochoscopic lithotomy: a single-center prospective study
publisher Frontiers Media S.A.
publishDate 2021
url https://doaj.org/article/58f1e46b4831420486a0058ad47bf9d9
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