Risk Factors for Early Recurrence of Gallstones in Patients Undergoing Laparoscopy Combined With Choledochoscopic Lithotomy: A Single-Center Prospective Study
Objective: For patients with gallstones, laparoscopy combined with choledochoscopic lithotomy is a therapeutic surgical option for preservation rather than the removal of the gallbladder. However, postoperative recurrence of gallstones is a key concern for both patients and surgeons. This prospectiv...
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Frontiers Media S.A.
2021
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oai:doaj.org-article:58f1e46b4831420486a0058ad47bf9d92021-11-30T17:12:27ZRisk Factors for Early Recurrence of Gallstones in Patients Undergoing Laparoscopy Combined With Choledochoscopic Lithotomy: A Single-Center Prospective Study2296-875X10.3389/fsurg.2021.759390https://doaj.org/article/58f1e46b4831420486a0058ad47bf9d92021-11-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fsurg.2021.759390/fullhttps://doaj.org/toc/2296-875XObjective: For patients with gallstones, laparoscopy combined with choledochoscopic lithotomy is a therapeutic surgical option for preservation rather than the removal of the gallbladder. However, postoperative recurrence of gallstones is a key concern for both patients and surgeons. This prospective study was performed to investigate the risk factors for early postoperative recurrence of gallstones.Methods: The clinical data of 466 patients were collected. Each patient was followed up for up to 2 years. The first follow-up visit occurred 4 months after the operation, and a follow-up visit was carried out every 6 months thereafter. The main goal of each visit was to confirm the presence or absence of gallbladder stones. The factors associated with gallstone recurrence were analyzed by univariate analysis and Cox regression.Results: In total, 466 eligible patients were included in the study, and 438 patients (180 men and 258 women) completed the 2-year postoperative follow-up. The follow-up rate was 94.0%. Recurrence of gallstones was detected in 5.71% (25/438) of the patients. Univariate analysis revealed five risk factors for the recurrence of gallstones. Multivariate Cox regression analysis showed that multiple gallstones, a gallbladder wall thickness of ≥4 mm, and a family history of gallbladder stones were the three predictive factors for postoperative recurrence of gallstones (P < 0.05).Conclusion: The overall 2-year recurrence rate of gallstones after the operation was 5.71%. Multiple gallstones, a gallbladder wall thickness of ≥4 mm, and a family history of gallstones were the three risk factors associated with early postoperative recurrence of gallstones.Bo WangAnhua HuangMin JiangHaidong LiWenqing BaoKan DingZhaoyan JiangGang ZhaoHai HuFrontiers Media S.A.articlegallstonelaparoscopy combined with choledochoscope lithotomyrisk factorsrecurrencefollow-upSurgeryRD1-811ENFrontiers in Surgery, Vol 8 (2021) |
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gallstone laparoscopy combined with choledochoscope lithotomy risk factors recurrence follow-up Surgery RD1-811 |
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gallstone laparoscopy combined with choledochoscope lithotomy risk factors recurrence follow-up Surgery RD1-811 Bo Wang Anhua Huang Min Jiang Haidong Li Wenqing Bao Kan Ding Zhaoyan Jiang Gang Zhao Hai Hu Risk Factors for Early Recurrence of Gallstones in Patients Undergoing Laparoscopy Combined With Choledochoscopic Lithotomy: A Single-Center Prospective Study |
description |
Objective: For patients with gallstones, laparoscopy combined with choledochoscopic lithotomy is a therapeutic surgical option for preservation rather than the removal of the gallbladder. However, postoperative recurrence of gallstones is a key concern for both patients and surgeons. This prospective study was performed to investigate the risk factors for early postoperative recurrence of gallstones.Methods: The clinical data of 466 patients were collected. Each patient was followed up for up to 2 years. The first follow-up visit occurred 4 months after the operation, and a follow-up visit was carried out every 6 months thereafter. The main goal of each visit was to confirm the presence or absence of gallbladder stones. The factors associated with gallstone recurrence were analyzed by univariate analysis and Cox regression.Results: In total, 466 eligible patients were included in the study, and 438 patients (180 men and 258 women) completed the 2-year postoperative follow-up. The follow-up rate was 94.0%. Recurrence of gallstones was detected in 5.71% (25/438) of the patients. Univariate analysis revealed five risk factors for the recurrence of gallstones. Multivariate Cox regression analysis showed that multiple gallstones, a gallbladder wall thickness of ≥4 mm, and a family history of gallbladder stones were the three predictive factors for postoperative recurrence of gallstones (P < 0.05).Conclusion: The overall 2-year recurrence rate of gallstones after the operation was 5.71%. Multiple gallstones, a gallbladder wall thickness of ≥4 mm, and a family history of gallstones were the three risk factors associated with early postoperative recurrence of gallstones. |
format |
article |
author |
Bo Wang Anhua Huang Min Jiang Haidong Li Wenqing Bao Kan Ding Zhaoyan Jiang Gang Zhao Hai Hu |
author_facet |
Bo Wang Anhua Huang Min Jiang Haidong Li Wenqing Bao Kan Ding Zhaoyan Jiang Gang Zhao Hai Hu |
author_sort |
Bo Wang |
title |
Risk Factors for Early Recurrence of Gallstones in Patients Undergoing Laparoscopy Combined With Choledochoscopic Lithotomy: A Single-Center Prospective Study |
title_short |
Risk Factors for Early Recurrence of Gallstones in Patients Undergoing Laparoscopy Combined With Choledochoscopic Lithotomy: A Single-Center Prospective Study |
title_full |
Risk Factors for Early Recurrence of Gallstones in Patients Undergoing Laparoscopy Combined With Choledochoscopic Lithotomy: A Single-Center Prospective Study |
title_fullStr |
Risk Factors for Early Recurrence of Gallstones in Patients Undergoing Laparoscopy Combined With Choledochoscopic Lithotomy: A Single-Center Prospective Study |
title_full_unstemmed |
Risk Factors for Early Recurrence of Gallstones in Patients Undergoing Laparoscopy Combined With Choledochoscopic Lithotomy: A Single-Center Prospective Study |
title_sort |
risk factors for early recurrence of gallstones in patients undergoing laparoscopy combined with choledochoscopic lithotomy: a single-center prospective study |
publisher |
Frontiers Media S.A. |
publishDate |
2021 |
url |
https://doaj.org/article/58f1e46b4831420486a0058ad47bf9d9 |
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