Chronic-Relapsing cutaneous leukocytoclastic vasculitis in a young patient with reduced EBV-specific T cell response using enzyme-linked immunospot (ELISPOT) assay successfully treated with Valaciclovir

Chronic-Relapsing cutaneous leukocytoclastic vasculitis in a young patient with reduced EBV-specific T cell response using enzyme-linked immunospot (ELISPOT) assay successfully treated with Valaciclovir

Among different pathogens, opportunistic viral infection caused by EBV is particularly relevant. This gammaherpesvirus, belonging to the Herpesviridae family, may complicate the disease course in different clinical settings by inducing pathological EBV pictures in patients with a defective immunolog...

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Autores principales: Caterina Foti, Elvira Favoino, Maria Scarasciulli, Anna Maria Colacicco, Hamidreza Jahantigh, Angela Stufano, Piero Lovreglio, Paola Mascia, Chiara Barlusconi, Federico Perosa, Paolo Romita, Agata Calvario
Formato: article
Lenguaje:EN
Publicado: Elsevier 2021
Materias:
Infectious and parasitic diseases
RC109-216
Acceso en línea:https://doaj.org/article/590131e0b4464b74b899bbfe4ad66ccb
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spelling oai:doaj.org-article:590131e0b4464b74b899bbfe4ad66ccb2021-11-20T05:06:13ZChronic-Relapsing cutaneous leukocytoclastic vasculitis in a young patient with reduced EBV-specific T cell response using enzyme-linked immunospot (ELISPOT) assay successfully treated with Valaciclovir2214-250910.1016/j.idcr.2021.e01331https://doaj.org/article/590131e0b4464b74b899bbfe4ad66ccb2021-01-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S2214250921002870https://doaj.org/toc/2214-2509Among different pathogens, opportunistic viral infection caused by EBV is particularly relevant. This gammaherpesvirus, belonging to the Herpesviridae family, may complicate the disease course in different clinical settings by inducing pathological EBV pictures in patients with a defective immunologic response. Our report evaluated EBV-specific T cell responses by IFN- γ ELISPOT assay, which revealed defective EBV specific immunological response.Caterina FotiElvira FavoinoMaria ScarasciulliAnna Maria ColaciccoHamidreza JahantighAngela StufanoPiero LovreglioPaola MasciaChiara BarlusconiFederico PerosaPaolo RomitaAgata CalvarioElsevierarticleInfectious and parasitic diseasesRC109-216ENIDCases, Vol 26, Iss , Pp e01331- (2021)
institution DOAJ
collection DOAJ
language EN
topic Infectious and parasitic diseases
RC109-216
spellingShingle Infectious and parasitic diseases
RC109-216
Caterina Foti
Elvira Favoino
Maria Scarasciulli
Anna Maria Colacicco
Hamidreza Jahantigh
Angela Stufano
Piero Lovreglio
Paola Mascia
Chiara Barlusconi
Federico Perosa
Paolo Romita
Agata Calvario
Chronic-Relapsing cutaneous leukocytoclastic vasculitis in a young patient with reduced EBV-specific T cell response using enzyme-linked immunospot (ELISPOT) assay successfully treated with Valaciclovir
description Among different pathogens, opportunistic viral infection caused by EBV is particularly relevant. This gammaherpesvirus, belonging to the Herpesviridae family, may complicate the disease course in different clinical settings by inducing pathological EBV pictures in patients with a defective immunologic response. Our report evaluated EBV-specific T cell responses by IFN- γ ELISPOT assay, which revealed defective EBV specific immunological response.
format article
author Caterina Foti
Elvira Favoino
Maria Scarasciulli
Anna Maria Colacicco
Hamidreza Jahantigh
Angela Stufano
Piero Lovreglio
Paola Mascia
Chiara Barlusconi
Federico Perosa
Paolo Romita
Agata Calvario
author_facet Caterina Foti
Elvira Favoino
Maria Scarasciulli
Anna Maria Colacicco
Hamidreza Jahantigh
Angela Stufano
Piero Lovreglio
Paola Mascia
Chiara Barlusconi
Federico Perosa
Paolo Romita
Agata Calvario
author_sort Caterina Foti
title Chronic-Relapsing cutaneous leukocytoclastic vasculitis in a young patient with reduced EBV-specific T cell response using enzyme-linked immunospot (ELISPOT) assay successfully treated with Valaciclovir
title_short Chronic-Relapsing cutaneous leukocytoclastic vasculitis in a young patient with reduced EBV-specific T cell response using enzyme-linked immunospot (ELISPOT) assay successfully treated with Valaciclovir
title_full Chronic-Relapsing cutaneous leukocytoclastic vasculitis in a young patient with reduced EBV-specific T cell response using enzyme-linked immunospot (ELISPOT) assay successfully treated with Valaciclovir
title_fullStr Chronic-Relapsing cutaneous leukocytoclastic vasculitis in a young patient with reduced EBV-specific T cell response using enzyme-linked immunospot (ELISPOT) assay successfully treated with Valaciclovir
title_full_unstemmed Chronic-Relapsing cutaneous leukocytoclastic vasculitis in a young patient with reduced EBV-specific T cell response using enzyme-linked immunospot (ELISPOT) assay successfully treated with Valaciclovir
title_sort chronic-relapsing cutaneous leukocytoclastic vasculitis in a young patient with reduced ebv-specific t cell response using enzyme-linked immunospot (elispot) assay successfully treated with valaciclovir
publisher Elsevier
publishDate 2021
url https://doaj.org/article/590131e0b4464b74b899bbfe4ad66ccb
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