SARS‐CoV‐2 infection shortly after BNT162b2 vaccination results in high anti‐spike antibody levels in nursing home residents and staff

Abstract Introduction One dose of a coronavirus disease 2019 (COVID‐19) vaccine can elicit high antibody titers in individuals who were previously infected by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2). However, it is unclear how a SARS‐CoV‐2 infection shortly after a first COVID‐1...

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Autores principales: Doris Urlaub, Natalie Wolfsdorff, Deniz Durak, Frank Renken, Carsten Watzl
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Lenguaje:EN
Publicado: Wiley 2021
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Acceso en línea:https://doaj.org/article/5902431511f448c2b60cff0972da2504
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spelling oai:doaj.org-article:5902431511f448c2b60cff0972da25042021-11-12T19:57:15ZSARS‐CoV‐2 infection shortly after BNT162b2 vaccination results in high anti‐spike antibody levels in nursing home residents and staff2050-452710.1002/iid3.525https://doaj.org/article/5902431511f448c2b60cff0972da25042021-12-01T00:00:00Zhttps://doi.org/10.1002/iid3.525https://doaj.org/toc/2050-4527Abstract Introduction One dose of a coronavirus disease 2019 (COVID‐19) vaccine can elicit high antibody titers in individuals who were previously infected by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2). However, it is unclear how a SARS‐CoV‐2 infection shortly after a first COVID‐19 vaccine dose affects antibody responses. Methods Here we investigate residents and staff of a nursing home, where a COVID‐19 outbreak occurred shortly after the first BNT162b2 immunization. Results and Conclusions Our data show that individuals who got infected as early as 10 days after their first immunization show antibody levels comparable to fully vaccinated individuals.Doris UrlaubNatalie WolfsdorffDeniz DurakFrank RenkenCarsten WatzlWileyarticleanti‐SARS‐CoV‐2 spike antibodiesCOVID‐19SARS‐CoV‐2vaccineImmunologic diseases. AllergyRC581-607ENImmunity, Inflammation and Disease, Vol 9, Iss 4, Pp 1702-1706 (2021)
institution DOAJ
collection DOAJ
language EN
topic anti‐SARS‐CoV‐2 spike antibodies
COVID‐19
SARS‐CoV‐2
vaccine
Immunologic diseases. Allergy
RC581-607
spellingShingle anti‐SARS‐CoV‐2 spike antibodies
COVID‐19
SARS‐CoV‐2
vaccine
Immunologic diseases. Allergy
RC581-607
Doris Urlaub
Natalie Wolfsdorff
Deniz Durak
Frank Renken
Carsten Watzl
SARS‐CoV‐2 infection shortly after BNT162b2 vaccination results in high anti‐spike antibody levels in nursing home residents and staff
description Abstract Introduction One dose of a coronavirus disease 2019 (COVID‐19) vaccine can elicit high antibody titers in individuals who were previously infected by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2). However, it is unclear how a SARS‐CoV‐2 infection shortly after a first COVID‐19 vaccine dose affects antibody responses. Methods Here we investigate residents and staff of a nursing home, where a COVID‐19 outbreak occurred shortly after the first BNT162b2 immunization. Results and Conclusions Our data show that individuals who got infected as early as 10 days after their first immunization show antibody levels comparable to fully vaccinated individuals.
format article
author Doris Urlaub
Natalie Wolfsdorff
Deniz Durak
Frank Renken
Carsten Watzl
author_facet Doris Urlaub
Natalie Wolfsdorff
Deniz Durak
Frank Renken
Carsten Watzl
author_sort Doris Urlaub
title SARS‐CoV‐2 infection shortly after BNT162b2 vaccination results in high anti‐spike antibody levels in nursing home residents and staff
title_short SARS‐CoV‐2 infection shortly after BNT162b2 vaccination results in high anti‐spike antibody levels in nursing home residents and staff
title_full SARS‐CoV‐2 infection shortly after BNT162b2 vaccination results in high anti‐spike antibody levels in nursing home residents and staff
title_fullStr SARS‐CoV‐2 infection shortly after BNT162b2 vaccination results in high anti‐spike antibody levels in nursing home residents and staff
title_full_unstemmed SARS‐CoV‐2 infection shortly after BNT162b2 vaccination results in high anti‐spike antibody levels in nursing home residents and staff
title_sort sars‐cov‐2 infection shortly after bnt162b2 vaccination results in high anti‐spike antibody levels in nursing home residents and staff
publisher Wiley
publishDate 2021
url https://doaj.org/article/5902431511f448c2b60cff0972da2504
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AT frankrenken sarscov2infectionshortlyafterbnt162b2vaccinationresultsinhighantispikeantibodylevelsinnursinghomeresidentsandstaff
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