Knockdown of lysine (K)-specific demethylase 2B KDM2B inhibits glycolysis and induces autophagy in lung squamous cell carcinoma cells by regulating the phosphatidylinositol 3-kinase/AKT/mammalian target of rapamycin pathway

Lung squamous cell carcinoma (LUSC) is a subtype of non-small cell lung cancer with poor prognosis. This study aimed to explore the role of KDM2B in the development of LUSC. The results of this study demonstrated that KDM2B was upregulated in LUSC tissues and cell lines. Knockdown of KDM2B reduced c...

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Bibliographic Details
Main Authors: Zhonghai Xie, Hongwei Li, Jin Zang
Format: article
Language:EN
Published: Taylor & Francis Group 2021
Subjects:
Online Access:https://doaj.org/article/590ec5d7227d45da80adf8d93bac7ec8
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