Genome-wide analysis in the mouse embryo reveals the importance of DNA methylation for transcription integrity

DNA methyltrasferases play important role during mouse embryo development. Here the authors reveal the consequences of genetic inactivation of Dnmt1, Dnmt3a and Dnmt3b on the methylome and transcriptome of mouse embryos genome-wide.

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Autores principales:	Thomas Dahlet, Andrea Argüeso Lleida, Hala Al Adhami, Michael Dumas, Ambre Bender, Richard P. Ngondo, Manon Tanguy, Judith Vallet, Ghislain Auclair, Anaïs F. Bardet, Michael Weber
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/590f66de9a5641b6a92e0860825a1341
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spelling	oai:doaj.org-article:590f66de9a5641b6a92e0860825a13412021-12-02T17:40:29ZGenome-wide analysis in the mouse embryo reveals the importance of DNA methylation for transcription integrity10.1038/s41467-020-16919-w2041-1723https://doaj.org/article/590f66de9a5641b6a92e0860825a13412020-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16919-whttps://doaj.org/toc/2041-1723DNA methyltrasferases play important role during mouse embryo development. Here the authors reveal the consequences of genetic inactivation of Dnmt1, Dnmt3a and Dnmt3b on the methylome and transcriptome of mouse embryos genome-wide.Thomas DahletAndrea Argüeso LleidaHala Al AdhamiMichael DumasAmbre BenderRichard P. NgondoManon TanguyJudith ValletGhislain AuclairAnaïs F. BardetMichael WeberNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Thomas Dahlet Andrea Argüeso Lleida Hala Al Adhami Michael Dumas Ambre Bender Richard P. Ngondo Manon Tanguy Judith Vallet Ghislain Auclair Anaïs F. Bardet Michael Weber Genome-wide analysis in the mouse embryo reveals the importance of DNA methylation for transcription integrity
description	DNA methyltrasferases play important role during mouse embryo development. Here the authors reveal the consequences of genetic inactivation of Dnmt1, Dnmt3a and Dnmt3b on the methylome and transcriptome of mouse embryos genome-wide.
format	article
author	Thomas Dahlet Andrea Argüeso Lleida Hala Al Adhami Michael Dumas Ambre Bender Richard P. Ngondo Manon Tanguy Judith Vallet Ghislain Auclair Anaïs F. Bardet Michael Weber
author_facet	Thomas Dahlet Andrea Argüeso Lleida Hala Al Adhami Michael Dumas Ambre Bender Richard P. Ngondo Manon Tanguy Judith Vallet Ghislain Auclair Anaïs F. Bardet Michael Weber
author_sort	Thomas Dahlet
title	Genome-wide analysis in the mouse embryo reveals the importance of DNA methylation for transcription integrity
title_short	Genome-wide analysis in the mouse embryo reveals the importance of DNA methylation for transcription integrity
title_full	Genome-wide analysis in the mouse embryo reveals the importance of DNA methylation for transcription integrity
title_fullStr	Genome-wide analysis in the mouse embryo reveals the importance of DNA methylation for transcription integrity
title_full_unstemmed	Genome-wide analysis in the mouse embryo reveals the importance of DNA methylation for transcription integrity
title_sort	genome-wide analysis in the mouse embryo reveals the importance of dna methylation for transcription integrity
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/590f66de9a5641b6a92e0860825a1341
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Genome-wide analysis in the mouse embryo reveals the importance of DNA methylation for transcription integrity

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