Body Mass Index and Melanoma Prognosis

Introduction: Obesity has been suggested as a risk factor in the progression of malignancies, including melanoma. Most studies defined obesity using body mass index (BMI), although the index is considered an imperfect measure of body composition. Objective: The aim of this article is to examine...

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Autores principales:	Nicoletta Cassano, Stefano Caccavale, Gino A. Vena, Giuseppe Argenziano
Formato:	article
Lenguaje:	EN
Publicado:	Mattioli1885 2021
Materias:	cutaneous melanoma body mass index Breslow thickness obesity Dermatology RL1-803
Acceso en línea:	https://doaj.org/article/591196c1a8044452864d5d64f4fa2d2e
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spelling	oai:doaj.org-article:591196c1a8044452864d5d64f4fa2d2e2021-11-15T15:17:25ZBody Mass Index and Melanoma Prognosis10.5826/dpc.1104a1062160-9381https://doaj.org/article/591196c1a8044452864d5d64f4fa2d2e2021-09-01T00:00:00Zhttps://dpcj.org/index.php/dpc/article/view/1631https://doaj.org/toc/2160-9381 Introduction: Obesity has been suggested as a risk factor in the progression of malignancies, including melanoma. Most studies defined obesity using body mass index (BMI), although the index is considered an imperfect measure of body composition. Objective: The aim of this article is to examine whether BMI can impact the prognosis of cutaneous melanoma, regardless of anti-tumor therapy. The relationship between BMI and specific prognostic factors in melanoma patients has been reviewed. Methods: Literature search was conducted on PubMed using the terms “melanoma” and “body mass index” or “obesity”. We selected articles, published up to 30 November 2020, examining the prognostic aspects of melanoma. Articles evaluating the risk and incidence of melanoma were excluded as well as studies regarding morbidity and complications following surgical procedures, or those performed in metastatic melanoma patients treated with anti-tumor therapies. Results: Mixed results have emerged from studies assessing the clinical outcomes in melanoma patients in relation to BMI. More consistent data seem to support the relationship between BMI and Breslow thickness. Conclusions: Studies that focus specifically on the link between obesity and melanoma prognosis are limited; further research is needed to deepen our knowledge on this link. Nicoletta CassanoStefano CaccavaleGino A. VenaGiuseppe ArgenzianoMattioli1885articlecutaneous melanomabody mass indexBreslow thicknessobesityDermatologyRL1-803ENDermatology Practical & Conceptual (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	cutaneous melanoma body mass index Breslow thickness obesity Dermatology RL1-803
spellingShingle	cutaneous melanoma body mass index Breslow thickness obesity Dermatology RL1-803 Nicoletta Cassano Stefano Caccavale Gino A. Vena Giuseppe Argenziano Body Mass Index and Melanoma Prognosis
description	Introduction: Obesity has been suggested as a risk factor in the progression of malignancies, including melanoma. Most studies defined obesity using body mass index (BMI), although the index is considered an imperfect measure of body composition. Objective: The aim of this article is to examine whether BMI can impact the prognosis of cutaneous melanoma, regardless of anti-tumor therapy. The relationship between BMI and specific prognostic factors in melanoma patients has been reviewed. Methods: Literature search was conducted on PubMed using the terms “melanoma” and “body mass index” or “obesity”. We selected articles, published up to 30 November 2020, examining the prognostic aspects of melanoma. Articles evaluating the risk and incidence of melanoma were excluded as well as studies regarding morbidity and complications following surgical procedures, or those performed in metastatic melanoma patients treated with anti-tumor therapies. Results: Mixed results have emerged from studies assessing the clinical outcomes in melanoma patients in relation to BMI. More consistent data seem to support the relationship between BMI and Breslow thickness. Conclusions: Studies that focus specifically on the link between obesity and melanoma prognosis are limited; further research is needed to deepen our knowledge on this link.
format	article
author	Nicoletta Cassano Stefano Caccavale Gino A. Vena Giuseppe Argenziano
author_facet	Nicoletta Cassano Stefano Caccavale Gino A. Vena Giuseppe Argenziano
author_sort	Nicoletta Cassano
title	Body Mass Index and Melanoma Prognosis
title_short	Body Mass Index and Melanoma Prognosis
title_full	Body Mass Index and Melanoma Prognosis
title_fullStr	Body Mass Index and Melanoma Prognosis
title_full_unstemmed	Body Mass Index and Melanoma Prognosis
title_sort	body mass index and melanoma prognosis
publisher	Mattioli1885
publishDate	2021
url	https://doaj.org/article/591196c1a8044452864d5d64f4fa2d2e
work_keys_str_mv	AT nicolettacassano bodymassindexandmelanomaprognosis AT stefanocaccavale bodymassindexandmelanomaprognosis AT ginoavena bodymassindexandmelanomaprognosis AT giuseppeargenziano bodymassindexandmelanomaprognosis
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Body Mass Index and Melanoma Prognosis

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