Direct conversion of human fibroblasts to brown adipocytes by small chemical compounds

Direct conversion of human fibroblasts to brown adipocytes by small chemical compounds

Abstract Brown adipocytes play an important role in human energy metabolism and prevention of obesity and diabetes. Induced pluripotent stem cells (iPSCs) represent a promising source for brown adipocytes; however, exogenous gene induction is generally required for iPSCs generation, which might caus...

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Autores principales: Yukimasa Takeda, Yoshinori Harada, Toshikazu Yoshikawa, Ping Dai
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/5912ca5dc598460a88e8292ed8005d9a
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