Streamlined ex vivo and in vivo genome editing in mouse embryos using recombinant adeno-associated viruses

CRISPR-Cas9 has been widely adopted for genetically manipulating rodents for scientific research. Here the authors transduce mouse embryos with CRISPR-Cas9 components using rAAVs in explant culture or in vivo to produce gene-edited animals.

Guardado en:

Detalles Bibliográficos
Autores principales:	Yeonsoo Yoon, Dan Wang, Phillip W. L. Tai, Joy Riley, Guangping Gao, Jaime A. Rivera-Pérez
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/591a750750ef423ca69ffb9deafcbf61
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:591a750750ef423ca69ffb9deafcbf61
record_format	dspace
spelling	oai:doaj.org-article:591a750750ef423ca69ffb9deafcbf612021-12-02T15:34:23ZStreamlined ex vivo and in vivo genome editing in mouse embryos using recombinant adeno-associated viruses10.1038/s41467-017-02706-72041-1723https://doaj.org/article/591a750750ef423ca69ffb9deafcbf612018-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02706-7https://doaj.org/toc/2041-1723CRISPR-Cas9 has been widely adopted for genetically manipulating rodents for scientific research. Here the authors transduce mouse embryos with CRISPR-Cas9 components using rAAVs in explant culture or in vivo to produce gene-edited animals.Yeonsoo YoonDan WangPhillip W. L. TaiJoy RileyGuangping GaoJaime A. Rivera-PérezNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Yeonsoo Yoon Dan Wang Phillip W. L. Tai Joy Riley Guangping Gao Jaime A. Rivera-Pérez Streamlined ex vivo and in vivo genome editing in mouse embryos using recombinant adeno-associated viruses
description	CRISPR-Cas9 has been widely adopted for genetically manipulating rodents for scientific research. Here the authors transduce mouse embryos with CRISPR-Cas9 components using rAAVs in explant culture or in vivo to produce gene-edited animals.
format	article
author	Yeonsoo Yoon Dan Wang Phillip W. L. Tai Joy Riley Guangping Gao Jaime A. Rivera-Pérez
author_facet	Yeonsoo Yoon Dan Wang Phillip W. L. Tai Joy Riley Guangping Gao Jaime A. Rivera-Pérez
author_sort	Yeonsoo Yoon
title	Streamlined ex vivo and in vivo genome editing in mouse embryos using recombinant adeno-associated viruses
title_short	Streamlined ex vivo and in vivo genome editing in mouse embryos using recombinant adeno-associated viruses
title_full	Streamlined ex vivo and in vivo genome editing in mouse embryos using recombinant adeno-associated viruses
title_fullStr	Streamlined ex vivo and in vivo genome editing in mouse embryos using recombinant adeno-associated viruses
title_full_unstemmed	Streamlined ex vivo and in vivo genome editing in mouse embryos using recombinant adeno-associated viruses
title_sort	streamlined ex vivo and in vivo genome editing in mouse embryos using recombinant adeno-associated viruses
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/591a750750ef423ca69ffb9deafcbf61
work_keys_str_mv	AT yeonsooyoon streamlinedexvivoandinvivogenomeeditinginmouseembryosusingrecombinantadenoassociatedviruses AT danwang streamlinedexvivoandinvivogenomeeditinginmouseembryosusingrecombinantadenoassociatedviruses AT phillipwltai streamlinedexvivoandinvivogenomeeditinginmouseembryosusingrecombinantadenoassociatedviruses AT joyriley streamlinedexvivoandinvivogenomeeditinginmouseembryosusingrecombinantadenoassociatedviruses AT guangpinggao streamlinedexvivoandinvivogenomeeditinginmouseembryosusingrecombinantadenoassociatedviruses AT jaimeariveraperez streamlinedexvivoandinvivogenomeeditinginmouseembryosusingrecombinantadenoassociatedviruses
_version_	1718386837428371456

Streamlined ex vivo and in vivo genome editing in mouse embryos using recombinant adeno-associated viruses

Ejemplares similares