SOME ASPECTS OF HIV-IMMUNOPATOLOGY IN INFECTED PERSONS LIVING IN THE FAR NORTH

The specific features of immune dysfunction in HIV-infected persons were studied, taking into account the stage of disease, the route of infection and climatic conditions of residence. Three hundred and. twenty-two HIV-infected patients aged from 17 to 57 years were examined. Of those with sexual tr...

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Autor principal:	E. S. Deshko
Formato:	article
Lenguaje:	RU
Publicado:	Scientific Сentre for Family Health and Human Reproduction Problems 2012
Materias:	hiv-infection immune status Science Q
Acceso en línea:	https://doaj.org/article/591f68cc2639443d8aecf61b58926d32
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id	oai:doaj.org-article:591f68cc2639443d8aecf61b58926d32
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spelling	oai:doaj.org-article:591f68cc2639443d8aecf61b58926d322021-11-23T06:14:23ZSOME ASPECTS OF HIV-IMMUNOPATOLOGY IN INFECTED PERSONS LIVING IN THE FAR NORTH2541-94202587-9596https://doaj.org/article/591f68cc2639443d8aecf61b58926d322012-09-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/1084https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596The specific features of immune dysfunction in HIV-infected persons were studied, taking into account the stage of disease, the route of infection and climatic conditions of residence. Three hundred and. twenty-two HIV-infected patients aged from 17 to 57 years were examined. Of those with sexual transmission were 185 (Group II), with the parenteral route of transmission - 137 (Group I). The findings suggest that there are pronounced and. significant cellular and. humoral changes: decreases in the level of CD4-!ymphocytes, in the immunoregulatory index (IRI), B-lymphocytes and. increased the content of CD3, CD8-lymphocytes, a rise in the concentration of IgG, IgM, IgE, and. increased formation of circulating immune complexes (CIC). These changes were observed in all subjects, but most pronounced in the group with the parenteral route of transmission, as well as in stage 4 A-B HIV infection. The degree of damage the immune system is more pronounced in comparison with the data obtained in other territories.E. S. DeshkoScientific Сentre for Family Health and Human Reproduction Problemsarticlehiv-infectionimmune statusScienceQRUActa Biomedica Scientifica, Vol 0, Iss 5(1), Pp 41-43 (2012)
institution	DOAJ
collection	DOAJ
language	RU
topic	hiv-infection immune status Science Q
spellingShingle	hiv-infection immune status Science Q E. S. Deshko SOME ASPECTS OF HIV-IMMUNOPATOLOGY IN INFECTED PERSONS LIVING IN THE FAR NORTH
description	The specific features of immune dysfunction in HIV-infected persons were studied, taking into account the stage of disease, the route of infection and climatic conditions of residence. Three hundred and. twenty-two HIV-infected patients aged from 17 to 57 years were examined. Of those with sexual transmission were 185 (Group II), with the parenteral route of transmission - 137 (Group I). The findings suggest that there are pronounced and. significant cellular and. humoral changes: decreases in the level of CD4-!ymphocytes, in the immunoregulatory index (IRI), B-lymphocytes and. increased the content of CD3, CD8-lymphocytes, a rise in the concentration of IgG, IgM, IgE, and. increased formation of circulating immune complexes (CIC). These changes were observed in all subjects, but most pronounced in the group with the parenteral route of transmission, as well as in stage 4 A-B HIV infection. The degree of damage the immune system is more pronounced in comparison with the data obtained in other territories.
format	article
author	E. S. Deshko
author_facet	E. S. Deshko
author_sort	E. S. Deshko
title	SOME ASPECTS OF HIV-IMMUNOPATOLOGY IN INFECTED PERSONS LIVING IN THE FAR NORTH
title_short	SOME ASPECTS OF HIV-IMMUNOPATOLOGY IN INFECTED PERSONS LIVING IN THE FAR NORTH
title_full	SOME ASPECTS OF HIV-IMMUNOPATOLOGY IN INFECTED PERSONS LIVING IN THE FAR NORTH
title_fullStr	SOME ASPECTS OF HIV-IMMUNOPATOLOGY IN INFECTED PERSONS LIVING IN THE FAR NORTH
title_full_unstemmed	SOME ASPECTS OF HIV-IMMUNOPATOLOGY IN INFECTED PERSONS LIVING IN THE FAR NORTH
title_sort	some aspects of hiv-immunopatology in infected persons living in the far north
publisher	Scientific Сentre for Family Health and Human Reproduction Problems
publishDate	2012
url	https://doaj.org/article/591f68cc2639443d8aecf61b58926d32
work_keys_str_mv	AT esdeshko someaspectsofhivimmunopatologyininfectedpersonslivinginthefarnorth
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SOME ASPECTS OF HIV-IMMUNOPATOLOGY IN INFECTED PERSONS LIVING IN THE FAR NORTH

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