Critical appraisal of loteprednol ointment, gel, and suspension in the treatment of postoperative inflammation and pain following ocular and corneal transplant surgery

Amir Pirouzian,1,2 E Randy Craven1,21Department of Ophthalmology, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia; 2Wilmer Eye Institute, Johns Hopkins University, Baltimore, MD, USAPurpose: To review comprehensively the available peer-reviewed published articles in the literature on lote...

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Autores principales:	Pirouzian A, Craven ER
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2014
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/592f1657244b489281aac21f3d75122f
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spelling	oai:doaj.org-article:592f1657244b489281aac21f3d75122f2021-12-02T01:25:39ZCritical appraisal of loteprednol ointment, gel, and suspension in the treatment of postoperative inflammation and pain following ocular and corneal transplant surgery1177-5483https://doaj.org/article/592f1657244b489281aac21f3d75122f2014-02-01T00:00:00Zhttp://www.dovepress.com/critical-appraisal-of-loteprednol-ointment-gel-and-suspension-in-the-t-a15746https://doaj.org/toc/1177-5483 Amir Pirouzian,1,2 E Randy Craven1,21Department of Ophthalmology, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia; 2Wilmer Eye Institute, Johns Hopkins University, Baltimore, MD, USAPurpose: To review comprehensively the available peer-reviewed published articles in the literature on loteprednol suspension, gel, and ointment in the treatment of ocular inflammation and pain following ocular surgery.Methods: We conducted a PubMed literature search review of all published articles on keywords associated with loteprednol etabonate and ocular surgery.Results: A total of 59 peer-reviewed articles were found in the literature. The focus of the majority of the articles was on the safety and efficacy of loteprednol etabonate 0.5% in post-operative control of inflammation and pain following cataract surgery. There were only three articles with a remote association between loteprednol etabonate and keratoplasty.Conclusion: Lotemax® ointment may also have potential as a first-line anti-inflammatory agent of choice in postoperative settings of strabismus and penetrating glaucoma, and following low-risk penetrating keratoplasty procedures.Keywords: loteprednol, inflammation, pain, keratoplasty, surgery, eyePirouzian ACraven ERDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2014, Iss default, Pp 379-387 (2014)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 Pirouzian A Craven ER Critical appraisal of loteprednol ointment, gel, and suspension in the treatment of postoperative inflammation and pain following ocular and corneal transplant surgery
description	Amir Pirouzian,1,2 E Randy Craven1,21Department of Ophthalmology, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia; 2Wilmer Eye Institute, Johns Hopkins University, Baltimore, MD, USAPurpose: To review comprehensively the available peer-reviewed published articles in the literature on loteprednol suspension, gel, and ointment in the treatment of ocular inflammation and pain following ocular surgery.Methods: We conducted a PubMed literature search review of all published articles on keywords associated with loteprednol etabonate and ocular surgery.Results: A total of 59 peer-reviewed articles were found in the literature. The focus of the majority of the articles was on the safety and efficacy of loteprednol etabonate 0.5% in post-operative control of inflammation and pain following cataract surgery. There were only three articles with a remote association between loteprednol etabonate and keratoplasty.Conclusion: Lotemax® ointment may also have potential as a first-line anti-inflammatory agent of choice in postoperative settings of strabismus and penetrating glaucoma, and following low-risk penetrating keratoplasty procedures.Keywords: loteprednol, inflammation, pain, keratoplasty, surgery, eye
format	article
author	Pirouzian A Craven ER
author_facet	Pirouzian A Craven ER
author_sort	Pirouzian A
title	Critical appraisal of loteprednol ointment, gel, and suspension in the treatment of postoperative inflammation and pain following ocular and corneal transplant surgery
title_short	Critical appraisal of loteprednol ointment, gel, and suspension in the treatment of postoperative inflammation and pain following ocular and corneal transplant surgery
title_full	Critical appraisal of loteprednol ointment, gel, and suspension in the treatment of postoperative inflammation and pain following ocular and corneal transplant surgery
title_fullStr	Critical appraisal of loteprednol ointment, gel, and suspension in the treatment of postoperative inflammation and pain following ocular and corneal transplant surgery
title_full_unstemmed	Critical appraisal of loteprednol ointment, gel, and suspension in the treatment of postoperative inflammation and pain following ocular and corneal transplant surgery
title_sort	critical appraisal of loteprednol ointment, gel, and suspension in the treatment of postoperative inflammation and pain following ocular and corneal transplant surgery
publisher	Dove Medical Press
publishDate	2014
url	https://doaj.org/article/592f1657244b489281aac21f3d75122f
work_keys_str_mv	AT pirouziana criticalappraisalofloteprednolointmentgelandsuspensioninthetreatmentofpostoperativeinflammationandpainfollowingocularandcornealtransplantsurgery AT cravener criticalappraisalofloteprednolointmentgelandsuspensioninthetreatmentofpostoperativeinflammationandpainfollowingocularandcornealtransplantsurgery
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Critical appraisal of loteprednol ointment, gel, and suspension in the treatment of postoperative inflammation and pain following ocular and corneal transplant surgery

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