Shavenbaby and Yorkie mediate Hippo signaling to protect adult stem cells from apoptosis
Organ regeneration by stem cells is required to compensate for tissue damage during aging, although how stem cells are maintained in adulthood is poorly understood. Here, the authors show in Drosophila that Shavenbaby interacts with Yorkie, a mediator of Hippo signalling, to ensure adult stem cell s...
Guardado en:
Autores principales: | , , , , , , , , , , , , , |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2018
|
Materias: | |
Acceso en línea: | https://doaj.org/article/5930b17e296243aa9c62f8dbc7b2397f |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
id |
oai:doaj.org-article:5930b17e296243aa9c62f8dbc7b2397f |
---|---|
record_format |
dspace |
spelling |
oai:doaj.org-article:5930b17e296243aa9c62f8dbc7b2397f2021-12-02T16:49:54ZShavenbaby and Yorkie mediate Hippo signaling to protect adult stem cells from apoptosis10.1038/s41467-018-07569-02041-1723https://doaj.org/article/5930b17e296243aa9c62f8dbc7b2397f2018-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07569-0https://doaj.org/toc/2041-1723Organ regeneration by stem cells is required to compensate for tissue damage during aging, although how stem cells are maintained in adulthood is poorly understood. Here, the authors show in Drosophila that Shavenbaby interacts with Yorkie, a mediator of Hippo signalling, to ensure adult stem cell survival.Jérôme BohèreAlexandra Mancheno-FerrisSandy Al HayekJennifer ZanetPhilippe ValentiKohsuke AkinoYuya YamabeSachi InagakiHélène Chanut-DelalandeSerge PlazaYuji KageyamaDani OsmanCédric PoleselloFrançois PayreNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-12 (2018) |
institution |
DOAJ |
collection |
DOAJ |
language |
EN |
topic |
Science Q |
spellingShingle |
Science Q Jérôme Bohère Alexandra Mancheno-Ferris Sandy Al Hayek Jennifer Zanet Philippe Valenti Kohsuke Akino Yuya Yamabe Sachi Inagaki Hélène Chanut-Delalande Serge Plaza Yuji Kageyama Dani Osman Cédric Polesello François Payre Shavenbaby and Yorkie mediate Hippo signaling to protect adult stem cells from apoptosis |
description |
Organ regeneration by stem cells is required to compensate for tissue damage during aging, although how stem cells are maintained in adulthood is poorly understood. Here, the authors show in Drosophila that Shavenbaby interacts with Yorkie, a mediator of Hippo signalling, to ensure adult stem cell survival. |
format |
article |
author |
Jérôme Bohère Alexandra Mancheno-Ferris Sandy Al Hayek Jennifer Zanet Philippe Valenti Kohsuke Akino Yuya Yamabe Sachi Inagaki Hélène Chanut-Delalande Serge Plaza Yuji Kageyama Dani Osman Cédric Polesello François Payre |
author_facet |
Jérôme Bohère Alexandra Mancheno-Ferris Sandy Al Hayek Jennifer Zanet Philippe Valenti Kohsuke Akino Yuya Yamabe Sachi Inagaki Hélène Chanut-Delalande Serge Plaza Yuji Kageyama Dani Osman Cédric Polesello François Payre |
author_sort |
Jérôme Bohère |
title |
Shavenbaby and Yorkie mediate Hippo signaling to protect adult stem cells from apoptosis |
title_short |
Shavenbaby and Yorkie mediate Hippo signaling to protect adult stem cells from apoptosis |
title_full |
Shavenbaby and Yorkie mediate Hippo signaling to protect adult stem cells from apoptosis |
title_fullStr |
Shavenbaby and Yorkie mediate Hippo signaling to protect adult stem cells from apoptosis |
title_full_unstemmed |
Shavenbaby and Yorkie mediate Hippo signaling to protect adult stem cells from apoptosis |
title_sort |
shavenbaby and yorkie mediate hippo signaling to protect adult stem cells from apoptosis |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/5930b17e296243aa9c62f8dbc7b2397f |
work_keys_str_mv |
AT jeromebohere shavenbabyandyorkiemediatehipposignalingtoprotectadultstemcellsfromapoptosis AT alexandramanchenoferris shavenbabyandyorkiemediatehipposignalingtoprotectadultstemcellsfromapoptosis AT sandyalhayek shavenbabyandyorkiemediatehipposignalingtoprotectadultstemcellsfromapoptosis AT jenniferzanet shavenbabyandyorkiemediatehipposignalingtoprotectadultstemcellsfromapoptosis AT philippevalenti shavenbabyandyorkiemediatehipposignalingtoprotectadultstemcellsfromapoptosis AT kohsukeakino shavenbabyandyorkiemediatehipposignalingtoprotectadultstemcellsfromapoptosis AT yuyayamabe shavenbabyandyorkiemediatehipposignalingtoprotectadultstemcellsfromapoptosis AT sachiinagaki shavenbabyandyorkiemediatehipposignalingtoprotectadultstemcellsfromapoptosis AT helenechanutdelalande shavenbabyandyorkiemediatehipposignalingtoprotectadultstemcellsfromapoptosis AT sergeplaza shavenbabyandyorkiemediatehipposignalingtoprotectadultstemcellsfromapoptosis AT yujikageyama shavenbabyandyorkiemediatehipposignalingtoprotectadultstemcellsfromapoptosis AT daniosman shavenbabyandyorkiemediatehipposignalingtoprotectadultstemcellsfromapoptosis AT cedricpolesello shavenbabyandyorkiemediatehipposignalingtoprotectadultstemcellsfromapoptosis AT francoispayre shavenbabyandyorkiemediatehipposignalingtoprotectadultstemcellsfromapoptosis |
_version_ |
1718383159552245760 |