Shavenbaby and Yorkie mediate Hippo signaling to protect adult stem cells from apoptosis

Organ regeneration by stem cells is required to compensate for tissue damage during aging, although how stem cells are maintained in adulthood is poorly understood. Here, the authors show in Drosophila that Shavenbaby interacts with Yorkie, a mediator of Hippo signalling, to ensure adult stem cell s...

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Autores principales: Jérôme Bohère, Alexandra Mancheno-Ferris, Sandy Al Hayek, Jennifer Zanet, Philippe Valenti, Kohsuke Akino, Yuya Yamabe, Sachi Inagaki, Hélène Chanut-Delalande, Serge Plaza, Yuji Kageyama, Dani Osman, Cédric Polesello, François Payre
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/5930b17e296243aa9c62f8dbc7b2397f
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spelling oai:doaj.org-article:5930b17e296243aa9c62f8dbc7b2397f2021-12-02T16:49:54ZShavenbaby and Yorkie mediate Hippo signaling to protect adult stem cells from apoptosis10.1038/s41467-018-07569-02041-1723https://doaj.org/article/5930b17e296243aa9c62f8dbc7b2397f2018-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07569-0https://doaj.org/toc/2041-1723Organ regeneration by stem cells is required to compensate for tissue damage during aging, although how stem cells are maintained in adulthood is poorly understood. Here, the authors show in Drosophila that Shavenbaby interacts with Yorkie, a mediator of Hippo signalling, to ensure adult stem cell survival.Jérôme BohèreAlexandra Mancheno-FerrisSandy Al HayekJennifer ZanetPhilippe ValentiKohsuke AkinoYuya YamabeSachi InagakiHélène Chanut-DelalandeSerge PlazaYuji KageyamaDani OsmanCédric PoleselloFrançois PayreNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Jérôme Bohère
Alexandra Mancheno-Ferris
Sandy Al Hayek
Jennifer Zanet
Philippe Valenti
Kohsuke Akino
Yuya Yamabe
Sachi Inagaki
Hélène Chanut-Delalande
Serge Plaza
Yuji Kageyama
Dani Osman
Cédric Polesello
François Payre
Shavenbaby and Yorkie mediate Hippo signaling to protect adult stem cells from apoptosis
description Organ regeneration by stem cells is required to compensate for tissue damage during aging, although how stem cells are maintained in adulthood is poorly understood. Here, the authors show in Drosophila that Shavenbaby interacts with Yorkie, a mediator of Hippo signalling, to ensure adult stem cell survival.
format article
author Jérôme Bohère
Alexandra Mancheno-Ferris
Sandy Al Hayek
Jennifer Zanet
Philippe Valenti
Kohsuke Akino
Yuya Yamabe
Sachi Inagaki
Hélène Chanut-Delalande
Serge Plaza
Yuji Kageyama
Dani Osman
Cédric Polesello
François Payre
author_facet Jérôme Bohère
Alexandra Mancheno-Ferris
Sandy Al Hayek
Jennifer Zanet
Philippe Valenti
Kohsuke Akino
Yuya Yamabe
Sachi Inagaki
Hélène Chanut-Delalande
Serge Plaza
Yuji Kageyama
Dani Osman
Cédric Polesello
François Payre
author_sort Jérôme Bohère
title Shavenbaby and Yorkie mediate Hippo signaling to protect adult stem cells from apoptosis
title_short Shavenbaby and Yorkie mediate Hippo signaling to protect adult stem cells from apoptosis
title_full Shavenbaby and Yorkie mediate Hippo signaling to protect adult stem cells from apoptosis
title_fullStr Shavenbaby and Yorkie mediate Hippo signaling to protect adult stem cells from apoptosis
title_full_unstemmed Shavenbaby and Yorkie mediate Hippo signaling to protect adult stem cells from apoptosis
title_sort shavenbaby and yorkie mediate hippo signaling to protect adult stem cells from apoptosis
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/5930b17e296243aa9c62f8dbc7b2397f
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