Application of bio-orthogonal proteome labeling to cell transplantation and heterochronic parabiosis

Clarifying the source of proteins in mixed biological environments, such as after transplantation or parabiosis, remains a challenge. Here, the authors address this need with a mouse strain that incorporates a methionine derivate into proteins, allowing for their detection using click chemistry and...

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Autores principales:	Yan Liu, Michael J. Conboy, Melod Mehdipour, Yutong Liu, Thanhtra P. Tran, Aaron Blotnick, Prasanna Rajan, Thalie Cavalcante Santos, Irina M. Conboy
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/593aea7e7dad473e959a3dab060fdf57
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spelling	oai:doaj.org-article:593aea7e7dad473e959a3dab060fdf572021-12-02T14:42:24ZApplication of bio-orthogonal proteome labeling to cell transplantation and heterochronic parabiosis10.1038/s41467-017-00698-y2041-1723https://doaj.org/article/593aea7e7dad473e959a3dab060fdf572017-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00698-yhttps://doaj.org/toc/2041-1723Clarifying the source of proteins in mixed biological environments, such as after transplantation or parabiosis, remains a challenge. Here, the authors address this need with a mouse strain that incorporates a methionine derivate into proteins, allowing for their detection using click chemistry and antibody arrays.Yan LiuMichael J. ConboyMelod MehdipourYutong LiuThanhtra P. TranAaron BlotnickPrasanna RajanThalie Cavalcante SantosIrina M. ConboyNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Yan Liu Michael J. Conboy Melod Mehdipour Yutong Liu Thanhtra P. Tran Aaron Blotnick Prasanna Rajan Thalie Cavalcante Santos Irina M. Conboy Application of bio-orthogonal proteome labeling to cell transplantation and heterochronic parabiosis
description	Clarifying the source of proteins in mixed biological environments, such as after transplantation or parabiosis, remains a challenge. Here, the authors address this need with a mouse strain that incorporates a methionine derivate into proteins, allowing for their detection using click chemistry and antibody arrays.
format	article
author	Yan Liu Michael J. Conboy Melod Mehdipour Yutong Liu Thanhtra P. Tran Aaron Blotnick Prasanna Rajan Thalie Cavalcante Santos Irina M. Conboy
author_facet	Yan Liu Michael J. Conboy Melod Mehdipour Yutong Liu Thanhtra P. Tran Aaron Blotnick Prasanna Rajan Thalie Cavalcante Santos Irina M. Conboy
author_sort	Yan Liu
title	Application of bio-orthogonal proteome labeling to cell transplantation and heterochronic parabiosis
title_short	Application of bio-orthogonal proteome labeling to cell transplantation and heterochronic parabiosis
title_full	Application of bio-orthogonal proteome labeling to cell transplantation and heterochronic parabiosis
title_fullStr	Application of bio-orthogonal proteome labeling to cell transplantation and heterochronic parabiosis
title_full_unstemmed	Application of bio-orthogonal proteome labeling to cell transplantation and heterochronic parabiosis
title_sort	application of bio-orthogonal proteome labeling to cell transplantation and heterochronic parabiosis
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/593aea7e7dad473e959a3dab060fdf57
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_version_	1718389689999687680

Application of bio-orthogonal proteome labeling to cell transplantation and heterochronic parabiosis

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