Exploring chemoselective S-to-N acyl transfer reactions in synthesis and chemical biology

The conversion of thioesters to amides via acyl transfer has become one of the most important synthetic techniques for the chemical synthesis and modification of proteins. This review discusses this S-to-N acyl transfer process, and highlights some of the key applications across chemistry and biolog...

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Autores principales:	Helen M. Burke, Lauren McSweeney, Eoin M. Scanlan
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/59417d48b6dc4b2da4db6f05832ae640
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spelling	oai:doaj.org-article:59417d48b6dc4b2da4db6f05832ae6402021-12-02T17:06:26ZExploring chemoselective S-to-N acyl transfer reactions in synthesis and chemical biology10.1038/ncomms156552041-1723https://doaj.org/article/59417d48b6dc4b2da4db6f05832ae6402017-05-01T00:00:00Zhttps://doi.org/10.1038/ncomms15655https://doaj.org/toc/2041-1723The conversion of thioesters to amides via acyl transfer has become one of the most important synthetic techniques for the chemical synthesis and modification of proteins. This review discusses this S-to-N acyl transfer process, and highlights some of the key applications across chemistry and biology.Helen M. BurkeLauren McSweeneyEoin M. ScanlanNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Helen M. Burke Lauren McSweeney Eoin M. Scanlan Exploring chemoselective S-to-N acyl transfer reactions in synthesis and chemical biology
description	The conversion of thioesters to amides via acyl transfer has become one of the most important synthetic techniques for the chemical synthesis and modification of proteins. This review discusses this S-to-N acyl transfer process, and highlights some of the key applications across chemistry and biology.
format	article
author	Helen M. Burke Lauren McSweeney Eoin M. Scanlan
author_facet	Helen M. Burke Lauren McSweeney Eoin M. Scanlan
author_sort	Helen M. Burke
title	Exploring chemoselective S-to-N acyl transfer reactions in synthesis and chemical biology
title_short	Exploring chemoselective S-to-N acyl transfer reactions in synthesis and chemical biology
title_full	Exploring chemoselective S-to-N acyl transfer reactions in synthesis and chemical biology
title_fullStr	Exploring chemoselective S-to-N acyl transfer reactions in synthesis and chemical biology
title_full_unstemmed	Exploring chemoselective S-to-N acyl transfer reactions in synthesis and chemical biology
title_sort	exploring chemoselective s-to-n acyl transfer reactions in synthesis and chemical biology
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/59417d48b6dc4b2da4db6f05832ae640
work_keys_str_mv	AT helenmburke exploringchemoselectivestonacyltransferreactionsinsynthesisandchemicalbiology AT laurenmcsweeney exploringchemoselectivestonacyltransferreactionsinsynthesisandchemicalbiology AT eoinmscanlan exploringchemoselectivestonacyltransferreactionsinsynthesisandchemicalbiology
_version_	1718381612854411264

Exploring chemoselective S-to-N acyl transfer reactions in synthesis and chemical biology

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