Age-associated changes in oxidative stress and NAD+ metabolism in human tissue.
Nicotinamide adenine dinucleotide (NAD(+)) is an essential electron transporter in mitochondrial respiration and oxidative phosphorylation. In genomic DNA, NAD(+) also represents the sole substrate for the nuclear repair enzyme, poly(ADP-ribose) polymerase (PARP) and the sirtuin family of NAD-depend...
Guardado en:
Autores principales: | Hassina Massudi, Ross Grant, Nady Braidy, Jade Guest, Bruce Farnsworth, Gilles J Guillemin |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2012
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Materias: | |
Acceso en línea: | https://doaj.org/article/595d60ab48ee4604b97b3889815f5503 |
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