An in vitro investigation to understand the synergistic role of MMPs-1 and 9 on articular cartilage biomechanical properties

Abstract Matrix metalloproteinases (MMPs) play a crucial role in enzymatically digesting cartilage extracellular matrix (ECM) components, resulting in degraded cartilage with altered mechanical loading capacity. Overexpression of MMPs is often caused by trauma, physiologic conditions and by disease....

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Bibliographic Details
Main Authors: Allison Mixon, Andrew Savage, Ahmed Suparno Bahar-Moni, Malek Adouni, Tanvir Faisal
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
R
Q
Online Access:https://doaj.org/article/59625733aa864725a8913e40ab61bd3c
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