Association of Glycosylated Hemoglobin A1c Level With Sudden Sensorineural Hearing Loss: A Prospective Study

Glycosylated hemoglobin A1c (HbA1c) level has strong relevance to microvascular disorders, which are also thought to be the current main aspect of sudden sensorineural hearing loss (SSNHL), so we aim to elucidate the association of the HbA1c level with the severity, types, and prognosis of SSNHL. In...

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Autores principales: Ying Shen, Zhong Zheng, Lili Xiao, Chengqi Liu, Jingyi Guo, Zhengnong Chen, Yaqin Wu, Haibo Shi, Zhen Zhang, Di Qian, Yanmei Feng, Shankai Yin
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Publicado: Frontiers Media S.A. 2021
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Acceso en línea:https://doaj.org/article/5962e6df7361447b88d9b5fe356a2198
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spelling oai:doaj.org-article:5962e6df7361447b88d9b5fe356a21982021-11-18T12:31:02ZAssociation of Glycosylated Hemoglobin A1c Level With Sudden Sensorineural Hearing Loss: A Prospective Study1664-239210.3389/fendo.2021.763021https://doaj.org/article/5962e6df7361447b88d9b5fe356a21982021-11-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fendo.2021.763021/fullhttps://doaj.org/toc/1664-2392Glycosylated hemoglobin A1c (HbA1c) level has strong relevance to microvascular disorders, which are also thought to be the current main aspect of sudden sensorineural hearing loss (SSNHL), so we aim to elucidate the association of the HbA1c level with the severity, types, and prognosis of SSNHL. In this study, comparative analyses based on propensity score matching of the severity, types, and prognosis of SSNHL with the HbA1c level in 116 patients diagnosed as SSNHL were conducted, where they were divided into diabetes mellitus (DM) group and non-DM group. We finally found that, among patients with SSNHL, diabetic patients had a higher HbA1c level, more severe hearing loss, and poorer prognosis than non-diabetic patients. The HbA1c level was found to be significantly correlated with the severity and types of SSNHL, while no strong relevance was found between the higher HbA1c level and the poorer prognosis of SSNHL.Ying ShenYing ShenZhong ZhengZhong ZhengLili XiaoLili XiaoChengqi LiuChengqi LiuJingyi GuoZhengnong ChenZhengnong ChenYaqin WuYaqin WuHaibo ShiHaibo ShiZhen ZhangZhen ZhangDi QianYanmei FengYanmei FengShankai YinShankai YinFrontiers Media S.A.articlesudden sensorineural hearing lossdiabetes mellitusglycosylated hemoglobin A1cmicrovascular disorderspropensity score matchingDiseases of the endocrine glands. Clinical endocrinologyRC648-665ENFrontiers in Endocrinology, Vol 12 (2021)
institution DOAJ
collection DOAJ
language EN
topic sudden sensorineural hearing loss
diabetes mellitus
glycosylated hemoglobin A1c
microvascular disorders
propensity score matching
Diseases of the endocrine glands. Clinical endocrinology
RC648-665
spellingShingle sudden sensorineural hearing loss
diabetes mellitus
glycosylated hemoglobin A1c
microvascular disorders
propensity score matching
Diseases of the endocrine glands. Clinical endocrinology
RC648-665
Ying Shen
Ying Shen
Zhong Zheng
Zhong Zheng
Lili Xiao
Lili Xiao
Chengqi Liu
Chengqi Liu
Jingyi Guo
Zhengnong Chen
Zhengnong Chen
Yaqin Wu
Yaqin Wu
Haibo Shi
Haibo Shi
Zhen Zhang
Zhen Zhang
Di Qian
Yanmei Feng
Yanmei Feng
Shankai Yin
Shankai Yin
Association of Glycosylated Hemoglobin A1c Level With Sudden Sensorineural Hearing Loss: A Prospective Study
description Glycosylated hemoglobin A1c (HbA1c) level has strong relevance to microvascular disorders, which are also thought to be the current main aspect of sudden sensorineural hearing loss (SSNHL), so we aim to elucidate the association of the HbA1c level with the severity, types, and prognosis of SSNHL. In this study, comparative analyses based on propensity score matching of the severity, types, and prognosis of SSNHL with the HbA1c level in 116 patients diagnosed as SSNHL were conducted, where they were divided into diabetes mellitus (DM) group and non-DM group. We finally found that, among patients with SSNHL, diabetic patients had a higher HbA1c level, more severe hearing loss, and poorer prognosis than non-diabetic patients. The HbA1c level was found to be significantly correlated with the severity and types of SSNHL, while no strong relevance was found between the higher HbA1c level and the poorer prognosis of SSNHL.
format article
author Ying Shen
Ying Shen
Zhong Zheng
Zhong Zheng
Lili Xiao
Lili Xiao
Chengqi Liu
Chengqi Liu
Jingyi Guo
Zhengnong Chen
Zhengnong Chen
Yaqin Wu
Yaqin Wu
Haibo Shi
Haibo Shi
Zhen Zhang
Zhen Zhang
Di Qian
Yanmei Feng
Yanmei Feng
Shankai Yin
Shankai Yin
author_facet Ying Shen
Ying Shen
Zhong Zheng
Zhong Zheng
Lili Xiao
Lili Xiao
Chengqi Liu
Chengqi Liu
Jingyi Guo
Zhengnong Chen
Zhengnong Chen
Yaqin Wu
Yaqin Wu
Haibo Shi
Haibo Shi
Zhen Zhang
Zhen Zhang
Di Qian
Yanmei Feng
Yanmei Feng
Shankai Yin
Shankai Yin
author_sort Ying Shen
title Association of Glycosylated Hemoglobin A1c Level With Sudden Sensorineural Hearing Loss: A Prospective Study
title_short Association of Glycosylated Hemoglobin A1c Level With Sudden Sensorineural Hearing Loss: A Prospective Study
title_full Association of Glycosylated Hemoglobin A1c Level With Sudden Sensorineural Hearing Loss: A Prospective Study
title_fullStr Association of Glycosylated Hemoglobin A1c Level With Sudden Sensorineural Hearing Loss: A Prospective Study
title_full_unstemmed Association of Glycosylated Hemoglobin A1c Level With Sudden Sensorineural Hearing Loss: A Prospective Study
title_sort association of glycosylated hemoglobin a1c level with sudden sensorineural hearing loss: a prospective study
publisher Frontiers Media S.A.
publishDate 2021
url https://doaj.org/article/5962e6df7361447b88d9b5fe356a2198
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