Differential diagnosis and treatment of primary peritoneal cancer and mesothelioma

Primary peritoneal cancer and mesothelioma belong to one nosological structure namely primary malignant neoplasms of the peritoneum. Such pathologies, regardless of their morphological differences, have the following in common: low incidence, the absence of pathognomonic signs, similarity of radiolo...

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Autores principales:	Amir G. Abdullaev, Nikolay A. Kozlov, Nikolay K. Schakhpazyan, Anna V. Tsigankova
Formato:	article
Lenguaje:	RU
Publicado:	IP Habib O.N. 2021
Materias:	primary neoplasms of the peritoneum primary cancer of the peritoneum peritoneal mesothelioma Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Acceso en línea:	https://doaj.org/article/5967ccb62faf436687f75d1f5b38f13b
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spelling	oai:doaj.org-article:5967ccb62faf436687f75d1f5b38f13b2021-11-30T17:03:34ZDifferential diagnosis and treatment of primary peritoneal cancer and mesothelioma1815-14341815-144210.26442/18151434.2020.4.200271https://doaj.org/article/5967ccb62faf436687f75d1f5b38f13b2021-02-01T00:00:00Zhttps://modernonco.orscience.ru/1815-1434/article/viewFile/61162/44251https://doaj.org/toc/1815-1434https://doaj.org/toc/1815-1442Primary peritoneal cancer and mesothelioma belong to one nosological structure namely primary malignant neoplasms of the peritoneum. Such pathologies, regardless of their morphological differences, have the following in common: low incidence, the absence of pathognomonic signs, similarity of radiological signs and lack of knowledge regarding prognostic factors. Considering the low incidence, reliable differential diagnostic indicators are not currently set up, which makes it substantially more complicated to timely formulate the diagnosis. On the contrary, more often we could reveal the cases where the wrong treatment strategy has been chosen, the absence of unified maintenance algorithm, when in fact a history of a patient`s present illness represents an individual creation of a particular doctor. On the other hand, the independent experience of a number of clinics does not exceed a few observations, which does not allow doctors to confidently navigate the problem. Thus, the relevance of conducting multicenter and perhaps prospective randomized scientific research studies with the aim of unified algorithm elaboration of the management of patients with primary peritoneal neoplasms has become imminent. The traditional algorithms for this pathology treatment embrace surgical step and systemic or intracavitary chemotherapy, where treatment sequence could be varied and foremost depends on a disease spread. In order to determine the extent of intraperitoneal dissemination the Sugarbaker peritoneal carcinomatosis index (PCI) is currently used, it also has been proved that one of the main prognostic factors is the degree of cytoreduction completeness. In the article below, we have tried to provide modern concepts of primary peritoneal cancer and peritoneal mesothelioma diagnosis, treatment and prognosis.Amir G. AbdullaevNikolay A. KozlovNikolay K. SchakhpazyanAnna V. TsigankovaIP Habib O.N.articleprimary neoplasms of the peritoneumprimary cancer of the peritoneumperitoneal mesotheliomaNeoplasms. Tumors. Oncology. Including cancer and carcinogensRC254-282RUСовременная онкология, Vol 22, Iss 4, Pp 91-95 (2021)
institution	DOAJ
collection	DOAJ
language	RU
topic	primary neoplasms of the peritoneum primary cancer of the peritoneum peritoneal mesothelioma Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
spellingShingle	primary neoplasms of the peritoneum primary cancer of the peritoneum peritoneal mesothelioma Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282 Amir G. Abdullaev Nikolay A. Kozlov Nikolay K. Schakhpazyan Anna V. Tsigankova Differential diagnosis and treatment of primary peritoneal cancer and mesothelioma
description	Primary peritoneal cancer and mesothelioma belong to one nosological structure namely primary malignant neoplasms of the peritoneum. Such pathologies, regardless of their morphological differences, have the following in common: low incidence, the absence of pathognomonic signs, similarity of radiological signs and lack of knowledge regarding prognostic factors. Considering the low incidence, reliable differential diagnostic indicators are not currently set up, which makes it substantially more complicated to timely formulate the diagnosis. On the contrary, more often we could reveal the cases where the wrong treatment strategy has been chosen, the absence of unified maintenance algorithm, when in fact a history of a patient`s present illness represents an individual creation of a particular doctor. On the other hand, the independent experience of a number of clinics does not exceed a few observations, which does not allow doctors to confidently navigate the problem. Thus, the relevance of conducting multicenter and perhaps prospective randomized scientific research studies with the aim of unified algorithm elaboration of the management of patients with primary peritoneal neoplasms has become imminent. The traditional algorithms for this pathology treatment embrace surgical step and systemic or intracavitary chemotherapy, where treatment sequence could be varied and foremost depends on a disease spread. In order to determine the extent of intraperitoneal dissemination the Sugarbaker peritoneal carcinomatosis index (PCI) is currently used, it also has been proved that one of the main prognostic factors is the degree of cytoreduction completeness. In the article below, we have tried to provide modern concepts of primary peritoneal cancer and peritoneal mesothelioma diagnosis, treatment and prognosis.
format	article
author	Amir G. Abdullaev Nikolay A. Kozlov Nikolay K. Schakhpazyan Anna V. Tsigankova
author_facet	Amir G. Abdullaev Nikolay A. Kozlov Nikolay K. Schakhpazyan Anna V. Tsigankova
author_sort	Amir G. Abdullaev
title	Differential diagnosis and treatment of primary peritoneal cancer and mesothelioma
title_short	Differential diagnosis and treatment of primary peritoneal cancer and mesothelioma
title_full	Differential diagnosis and treatment of primary peritoneal cancer and mesothelioma
title_fullStr	Differential diagnosis and treatment of primary peritoneal cancer and mesothelioma
title_full_unstemmed	Differential diagnosis and treatment of primary peritoneal cancer and mesothelioma
title_sort	differential diagnosis and treatment of primary peritoneal cancer and mesothelioma
publisher	IP Habib O.N.
publishDate	2021
url	https://doaj.org/article/5967ccb62faf436687f75d1f5b38f13b
work_keys_str_mv	AT amirgabdullaev differentialdiagnosisandtreatmentofprimaryperitonealcancerandmesothelioma AT nikolayakozlov differentialdiagnosisandtreatmentofprimaryperitonealcancerandmesothelioma AT nikolaykschakhpazyan differentialdiagnosisandtreatmentofprimaryperitonealcancerandmesothelioma AT annavtsigankova differentialdiagnosisandtreatmentofprimaryperitonealcancerandmesothelioma
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Differential diagnosis and treatment of primary peritoneal cancer and mesothelioma

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